公开(公告)号：US20230285697A1

公开(公告)日：2023-09-14

申请号：US18018365

申请日：2021-07-28

Applicant: Andrew Robert Cooper ,  Christopher George Blatchford ,  Stephen Howgill ,  Barzin Gavtash ,  Benjamin James Myatt ,  Hendrik Versteeg ,  Kerry Ward ,  Lee Michael Hodges ,  Sam Oladele Apoola ,  John Paul Bunting ,  KINDEVA DRUG DELIVERY L.P.

Inventor： Andrew Robert Cooper ,  Christopher George Blatchford ,  Stephen Howgill ,  Barzin Gavtash ,  Benjamin James Myatt ,  Hendrik Versteeg ,  Kerry Ward ,  Lee Michael Hodges ,  Sam Oladele Apoola ,  John Paul Bunting

IPC: A61M15/08 ,  A61M15/00

CPC classification number: A61M15/08 ,  A61M15/0065 ,  A61M15/0086

Abstract: Various embodiments of a device for delivery of a medicament and a method of utilizing such device are disclosed. The device can include a canister and an actuator. The actuator includes a housing receiving the canister; a valve block receiving a metering valve of the canister, the valve block defining an expansion chamber for passage of propellant and medicament expelled from the canister; and a nosepiece for insertion into a user's nostril, the nosepiece including a fluid passage and a delivery opening for expulsion of the propellant and medicament into the user's nostril. A flow path is defined through the actuator for passage of propellant and medicament from the canister and includes the expansion chamber, the fluid passage and the delivery opening. Further, the cross-sectional area of the flow path is greater than the lowest cross-sectional area of the metering valve at all points along the flow path.

公开(公告)号：US20230233777A1

公开(公告)日：2023-07-27

申请号：US17779028

申请日：2020-11-18

Applicant: KINDEVA DRUG DELIVERY L.P.

Inventor： John P. Bunting ,  Lee M. Hodges ,  Peter D. Hodson ,  Stephen J. Howgill ,  Adam J. Stuart ,  Kerry Ward

IPC: A61M15/00 ,  A61M16/20 ,  A61M16/00

CPC classification number: A61M15/0065 ,  A61M16/201 ,  A61M16/0003 ,  A61M2202/0225

Abstract: Various embodiments of a metered dose inhaler that includes a metering valve are disclosed. The inhaler includes a reservoir containing a pressurized formulation of medicament and carbon dioxide. The metering valve includes a metering chamber, a metering valve stem, and a metering valve stem seal having an opening through which the metering valve stem passes to form a dynamic seal between the metering valve stem and outside atmosphere. The metering valve stem seal has a Shore D hardness of 45 to 80 and its opening is adapted to be stretched wider by the metering valve stem passing through it than it would be absent the valve stem.