公开(公告)号：US20210002334A1

公开(公告)日：2021-01-07

申请号：US17026814

申请日：2020-09-21

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Ju Young LEE ,  In Seung JANG ,  Seohyun KIM ,  Sun-Chang KIM ,  Suk Chea JUNG ,  Jong Geon JEGAL

IPC: C07K14/395 ,  C12P19/56 ,  C12P33/20 ,  C12N15/81

Abstract: Provided are a recombinant yeast having improved ability to produce ginsenoside, which is prepared by overexpressing INO2 and INO4 or deleting OPT1 in a yeast having ability to produce ginsenoside, a method of preparing the yeast, and a method of producing ginsenoside by using the yeast.

公开(公告)号：US20240002888A1

公开(公告)日：2024-01-04

申请号：US18027984

申请日：2021-07-08

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Ju Young LEE ,  So Hee SON ,  Jae Eung KIM

IPC: C12P5/00 ,  C07K14/435

CPC classification number: C12P5/007 ,  C07K14/435

Abstract: Provided are a recombinant microorganism, a composition comprising the same, and a method of producing a target product by using the same, the recombinant microorganism comprising a polynucleotide encoding a target product-binding protein fused to a secretion signal sequence.

公开(公告)号：US20180319852A1

公开(公告)日：2018-11-08

申请号：US15880838

申请日：2018-01-26

Applicant: INTELLIGENT SYNTHETIC BIOLOGY CENTER ,  KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Ju Young LEE ,  In Seung JANG ,  Seohyun KIM ,  Sun-Chang KIM ,  Suk Chea JUNG ,  Jong Geon JEGAL

IPC: C07K14/395 ,  C12P33/20 ,  C12P19/56

CPC classification number: C07K14/395 ,  C12N15/81 ,  C12N2501/60 ,  C12P19/56 ,  C12P33/20

Abstract: Provided are a recombinant yeast having improved ability to produce ginsenoside, which is prepared by overexpressing INO2 and INO4 or deleting OPT1 in a yeast having ability to produce ginsenoside, a method of preparing the yeast, and a method of producing ginsenoside by using the yeast.

公开(公告)号：US20250027095A1

公开(公告)日：2025-01-23

申请号：US18776896

申请日：2024-07-18

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Ju Young LEE ,  Mi Ri KIM ,  Myung Hyun NOH ,  Soo Young MOON

IPC: C12N15/70 ,  C07K14/47 ,  C12N1/20 ,  C12N9/22 ,  C12N15/113

Abstract: Disclosed are a plasmid comprising dxCas9 and a CRP derivative for controlling the expression of a target gene, a recombinant strain transformed with the plasmid, a preparation method therefor, a target gene control system, and a method for controlling the expression of a target gene, wherein the plasmid, recombinant strain, and expression control system according to the present invention can improve the production of high-value-added substances by construction of a system for simultaneously and multiply controlling the expression of target genes.