公开(公告)号：US20160266104A1

公开(公告)日：2016-09-15

申请号：US15069063

申请日：2016-03-14

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Yung Doug SUH ,  Jwa Min NAM ,  Dong Kwon LIM

IPC: G01N33/543 ,  G01N33/53 ,  G01N33/552 ,  C12Q1/68 ,  G01N33/553

CPC classification number: G01N33/54346 ,  C12Q1/6816 ,  C12Q1/6825 ,  G01N33/553 ,  G01N33/582 ,  G01N33/587 ,  C12Q2563/137 ,  C12Q2563/143 ,  C12Q2563/149 ,  C12Q2565/519 ,  C12Q2565/632

Abstract: The present invention relates to a nanoparticle heterodimer in which Raman-active molecules are located at a binding portion of the nanoparticle heterodimer, and more particularly, to a core-shell nanoparticle heterodimer comprising: a gold or silver core having a surface to which oligonucleotides are bonded; and a gold or silver shell covering the core. In addition, the present invention relates to the core-shell nanoparticle dimer, to a method for preparing same, and to the use thereof.

Abstract translation: 本发明涉及纳米颗粒异二聚体，其中拉曼活性分子位于纳米颗粒异二聚体的结合部分，更具体地涉及核 - 壳纳米颗粒异源二聚体，其包含：具有寡核苷酸的表面的金或银核 保税 以及覆盖芯的金或银壳。 此外，本发明涉及核 - 壳纳米颗粒二聚体，其制备方法及其用途。

公开(公告)号：US20200217798A1

公开(公告)日：2020-07-09

申请号：US16730386

申请日：2019-12-30

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Yung Doug SUH

IPC: G01N21/65 ,  G01N33/53 ,  G01N33/543 ,  G01N33/569

Abstract: The present invention relates to a diagnostic kit for sepsis, comprising: a first core gold nanoparticle having a target capture oligonucleotide coupled thereto, the target capture oligonucleotide binding complementarily to a portion of a sepsis pathogen-specific genome; and a second core gold nanoparticle to which a target capture oligonucleotide having a Raman-active molecule coupled to one end thereof is coupled via the other end thereof, the target capture oligonucleotide including a sequence complementary to a portion of the sepsis pathogen-specific genome which does not overlap with, but is successive to the portion for the first gold nanoparticle, and a method for diagnosis of sepsis, using the same.

公开(公告)号：US20180177899A1

公开(公告)日：2018-06-28

申请号：US15580977

申请日：2016-05-19

Applicant: Korea Basic Science Institute ,  Korea Research Institute Of Chemical Technology

Inventor： Kwan Soo HONG ,  Hye Sun PARK ,  Sang Hwan NAM ,  Yung Doug SUH

IPC: A61K49/18

CPC classification number: A61K49/1821 ,  A61K49/0023 ,  A61K49/0034 ,  A61K49/0067 ,  A61K49/0093 ,  A61K49/1833 ,  A61K49/1839

Abstract: Provided are a hydrophilic particle, a method for manufacturing the same, and a contrasting agent using the same. More specifically, the hydrophilic particle according to the inventive concept may include a hydrophobic particle, and an amphiphilic organic dye directly absorbed on a surface of the hydrophobic particle. In this case, the hydrophobic particle includes a center particle, and a hydrophobic ligand covering a surface of the center particle, and the amphiphilic organic dye may be combined to the hydrophobic ligand by a hydrophobic interaction. The hydrophilic particle may have a surface zeta potential lower than a surface zeta potential of the amphiphilic organic dye.

公开(公告)号：US20160097887A1

公开(公告)日：2016-04-07

申请号：US14787141

申请日：2014-02-13

Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY

Inventor： Seung Min JIN ,  Il Seung YANG ,  Yung Doug SUH ,  Sang Hwan NAM ,  Yu Jin JUNG ,  Hae Mi LEE ,  Yun Mi BAE ,  So Jeong PARK ,  Yu Sic KIM

IPC: G02B5/20

CPC classification number: G02B5/20 ,  G01J1/0414 ,  G01J1/0448 ,  G01J3/12 ,  G01J2003/1243 ,  G01J2003/1247

Abstract: Provided is a monochromatization device for easily selecting light having a specific wavelength, comprising: a first broadband filter arranged to have a first rotational angle with respect to an incident direction of light to enable a first wavelength band to pass therethrough with respect to the incident light; a second broadband filter arranged to have a second rotational angle with respect to an incident direction of light to enable a second wavelength band to pass therethrough with respect to the light passing through the first broadband filter; and a path compensation unit for adjusting a light path so that the light path passing through the second broadband filter is the same as a path of the light incident to the first broadband filter. Accordingly, the output light efficiency for the incident light is increased and the required specific wavelength can be more easily selected.

Abstract translation: 提供一种用于容易地选择具有特定波长的光的单色化装置，包括：第一宽带滤光器，被布置成相对于光的入射方向具有第一旋转角度，以使得第一波长带相对于入射光能够通过 ; 第二宽带滤波器，被布置成相对于光的入射方向具有第二旋转角度，以使第二波长带相对于穿过所述第一宽带滤光器的光线通过; 以及路径补偿单元，用于调整光路，使得穿过第二宽带滤波器的光路与入射到第一宽带滤波器的光的路径相同。 因此，入射光的输出光效率增加，并且可以更容易地选择所需的特定波长。