公开(公告)号：US20190143310A1

公开(公告)日：2019-05-16

申请号：US16314572

申请日：2017-06-28

Applicant: King Abdullah University of Science and Technology

Inventor： Kuo-Wei HUANG ,  Chao GUAN ,  Yupeng PAN ,  Jinsong HU ,  Huaifeng LI

IPC: B01J31/22 ,  C01B3/22 ,  B01J31/18 ,  H01M8/0612 ,  C07F15/00

Abstract: The present invention provides a class of catalyst compounds that can safely and effectively release hydrogen gas from a chemical substrate without producing either noxious byproducts or byproducts that will deactivate the catalyst. The present invention provides catalysts used to produce hydrogen that has a satisfactory and sufficient lifespan (measured by turnover number (TON)), that has stability in the presence of moisture, air, acid, or impurities, promote a rapid reaction rate, and remain stable under the reaction conditions required for an effective hydrogen production system. Described herein are compounds for use as catalysts, as well as methods for producing hydrogen from formic acid and/or a formate using the disclosed catalysts. The methods include contacting formic acid and/or a formate with a catalyst as described herein, as well as methods of producing formic acid and/or a formate using the disclosed catalyst and methods for generating electricity using the catalysts described herein.

公开(公告)号：US20200148641A1

公开(公告)日：2020-05-14

申请号：US16747245

申请日：2020-01-20

Applicant: King Abdullah University of Science and Technology

Inventor： Xinbo WANG ,  Zhiping LAI ,  Yupeng PAN ,  Kuowei HUANG

IPC: C07D209/86 ,  C07D471/14 ,  C07D471/22 ,  A61K31/403 ,  A61K31/5025

Abstract: The invention relates to novel N-(α-peroxy)carbazole compounds of Formula I and methods for use. The N-(α-peroxy)carbazole compounds described herein are useful for treating or preventing parasitic infections, bacterial infections, and cancer in subjects. The methods include administering an N-(α-peroxy)carbazole compound as described herein to a subject. Also described herein are methods for synthesizing N-(α-peroxy)carbazole compounds.

公开(公告)号：US20190135751A1

公开(公告)日：2019-05-09

申请号：US16099813

申请日：2017-05-10

Applicant: King Abdullah University of Science and Technology

Inventor： Xinbo WANG ,  Zhiping LAI ,  Yupeng PAN ,  Kuowei HUANG

IPC: C07D209/86 ,  C07D471/22 ,  A61K31/403 ,  A61K31/5025

CPC classification number: C07D209/86 ,  A61K31/403 ,  A61K31/5025 ,  C07D471/14 ,  C07D471/22

Abstract: The invention relates to novel N-(α-peroxy)carbazole compounds of Formula I and methods for use. (I) The N-(α-peroxy)carbazole compounds described herein are useful for treating or preventing parasitic infections, bacterial infections, and cancer in subjects. The methods include administering an N-(α-peroxy)carbazole compound as described herein to a subject. Also described herein are methods for synthesizing N-(α-peroxy)carbazole compounds.

公开(公告)号：US20190112267A1

公开(公告)日：2019-04-18

申请号：US16099853

申请日：2017-05-10

Applicant: King Abdullah University of Science and Technology

Inventor： Xinbo WANG ,  Zhiping LAI ,  Yupeng PAN ,  Kuowei HUANG ,  Zhigang WANG

IPC: C07D209/08 ,  A61K31/404 ,  A61K45/06 ,  C07D209/14 ,  A61K31/4045 ,  C07D209/26 ,  C07D403/06

Abstract: The invention relates to novel N-(α-peroxy)indole compounds of Formula I and methods for use. (I) The N-(α-peroxy)indole compounds described herein are useful for treating or preventing parastic infections, bacterial infections, and cancer in subjects. The methods include administering an N-(α-peroxy)indole compound as described herein to a subject. Also described herein are methods for synthesizing N-(α-peroxy)indole compounds.