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公开(公告)号:US20190071723A1
公开(公告)日:2019-03-07
申请号:US16182384
申请日:2018-11-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Phil WAGGONER , James A. BALL , Wolfgang HINZ , Michael L. MINTO , Scott PARKER , David M. COX , Alexander MASTROIANNI , Jeremy GRAY , Marc GLAZER , Kimberly GORRELL
IPC: C12Q1/6869 , G01N27/414
Abstract: A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.
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公开(公告)号:US20160279677A1
公开(公告)日:2016-09-29
申请号:US15079532
申请日:2016-03-24
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: James A. BALL , Phil WAGGONER , Scott PARKER
CPC classification number: B08B3/08 , B05D3/00 , B05D5/12 , B08B9/08 , C11D1/22 , C11D3/162 , C11D3/3418 , C11D3/43 , C11D7/34 , C11D7/5013 , C11D7/5022 , C11D11/0047 , G01N27/414 , G01N27/4145 , G01N27/4148 , H01L21/02057
Abstract: A method of treating a sensor array including a plurality of sensors and an isolation structure, where a sensor of the plurality of sensors has a sensor pad exposed at a surface of the sensor array and the isolation structure is disposed between the sensor pad and sensor pads of other sensors of the plurality of sensors, comprises exposing the sensor pad and the isolation structure to a non-aqueous organo-silicon solution including an organo-silicon compound and a first non-aqueous carrier; applying an acid solution including an organic acid and a second non-aqueous carrier to the sensor pad; and rinsing the acid solution from the sensor pad and the isolation structure.
Abstract translation: 一种处理包括多个传感器和隔离结构的传感器阵列的方法,其中所述多个传感器中的传感器具有在所述传感器阵列的表面处暴露的传感器垫,并且所述隔离结构设置在所述传感器垫和传感器垫之间 所述多个传感器中的其它传感器包括将所述传感器垫和所述隔离结构暴露于包括有机硅化合物和第一非水载体的非水有机硅溶液; 将包含有机酸和第二非水性载体的酸溶液施加到传感器垫; 以及从传感器垫和隔离结构冲洗酸溶液。
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公开(公告)号:US20240125733A1
公开(公告)日:2024-04-18
申请号:US18475640
申请日:2023-09-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Ronald L. CICERO , James A. BALL , Alexander MASTROIANN1 , Christina E. INMAN , Jeremy GRAY , Marc GLAZER , Yufang WANG , Joseph KOSCINSKI , Phil WAGGONER
IPC: G01N27/414
CPC classification number: G01N27/4145
Abstract: A sensor component includes a sensor including a sensor surface and a reaction site in cooperation with the sensor and exposing the sensor surface. The reaction site including a reaction site surface. A surface agent is bound to the reaction site surface or the sensor surface. The surface agent includes a surface active functional group reactive with Bronsted base or Lewis acid functionality on the reaction site surface or the sensor surface and including distal functionality that does not have a donor electron pair.
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公开(公告)号:US20210129192A1
公开(公告)日:2021-05-06
申请号:US17079756
申请日:2020-10-26
Applicant: Life Technologies Corporation
Inventor: James A. BALL , Phil WAGGONER , Scott T. PARKER
IPC: B08B3/08 , B08B9/08 , C11D3/16 , G01N27/414 , C11D3/34 , C11D3/43 , C11D1/22 , C11D11/00 , H01L21/02
Abstract: A method of treating a sensor array including a plurality of sensors and an isolation structure, where a sensor of the plurality of sensors has a sensor pad exposed at a surface of the sensor array and the isolation structure is disposed between the sensor pad and sensor pads of other sensors of the plurality of sensors, comprises exposing the sensor pad and the isolation structure to a non-aqueous organo-silicon solution including an organo-silicon compound and a first non-aqueous carrier; applying an acid solution including an organic acid and a second non-aqueous carrier to the sensor pad; and rinsing the acid solution from the sensor pad and the isolation structure.
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公开(公告)号:US20200090947A1
公开(公告)日:2020-03-19
申请号:US16687630
申请日:2019-11-18
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Phil WAGGONER , Jordan OWENS
IPC: H01L21/311 , G01N27/414 , H01L21/02 , H01L21/027 , H01L21/285 , H01L21/3213
Abstract: A method for forming a well providing access to a sensor pad includes patterning a first photoresist layer over a dielectric structure disposed over the sensor pad; etching a first access into the dielectric structure and over the sensor pad, the first access having a first characteristic diameter; patterning a second photoresist layer over the dielectric structure; and etching a second access over the dielectric structure and over the sensor pad. The second access has a second characteristic diameter. The first and second accesses overlapping. A diameter ratio of the first characteristic diameter to the second characteristic diameter is not greater than 0.7. The first access exposes the sensor pad. The second access has a bottom depth less than a bottom depth of the first access.
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公开(公告)号:US20170095841A1
公开(公告)日:2017-04-06
申请号:US15387591
申请日:2016-12-21
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: James A. BALL , Phil WAGGONER , Scott PARKER
CPC classification number: B08B3/08 , B05D3/00 , B05D5/12 , B08B9/08 , C11D1/22 , C11D3/162 , C11D3/3418 , C11D3/43 , C11D7/34 , C11D7/5013 , C11D7/5022 , C11D11/0047 , G01N27/414 , G01N27/4145 , G01N27/4148 , H01L21/02057
Abstract: A method of treating a sensor array including a plurality of sensors and an isolation structure, where a sensor of the plurality of sensors has a sensor pad exposed at a surface of the sensor array and the isolation structure is disposed between the sensor pad and sensor pads of other sensors of the plurality of sensors, comprises exposing the sensor pad and the isolation structure to a non-aqueous organo-silicon solution including an organo-silicon compound and a first non-aqueous carrier; applying an acid solution including an organic acid and a second non-aqueous carrier to the sensor pad; and rinsing the acid solution from the sensor pad and the isolation structure.
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公开(公告)号:US20210325337A1
公开(公告)日:2021-10-21
申请号:US17267754
申请日:2019-08-16
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Phil WAGGONER
IPC: G01N27/414 , H01L21/203
Abstract: A method for manufacturing a sensor includes etching an insulator layer disposed over a substrate to define an opening exposing a sensor surface of a sensor disposed on the substrate, a native oxide forming on the sensor surface; sputtering the sensor surface with a noble gas to at least partially remove the native oxide from the sensor surface; and annealing the sensor surface in a hydrogen atmosphere.
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公开(公告)号:US20200055097A1
公开(公告)日:2020-02-20
申请号:US16663099
申请日:2019-10-24
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: James A. BALL , Phil WAGGONER , Scott PARKER
IPC: B08B3/08 , H01L21/02 , G01N27/414 , C11D11/00 , C11D1/22 , C11D3/43 , C11D3/34 , C11D3/16 , B08B9/08
Abstract: A method of treating a sensor array including a plurality of sensors and an isolation structure, where a sensor of the plurality of sensors has a sensor pad exposed at a surface of the sensor array and the isolation structure is disposed between the sensor pad and sensor pads of other sensors of the plurality of sensors, comprises exposing the sensor pad and the isolation structure to a non-aqueous organo-silicon solution including an organo-silicon compound and a first non-aqueous carrier; applying an acid solution including an organic acid and a second non-aqueous carrier to the sensor pad; and rinsing the acid solution from the sensor pad and the isolation structure.
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公开(公告)号:US20190204293A1
公开(公告)日:2019-07-04
申请号:US16229272
申请日:2018-12-21
Applicant: Life Technologies Corporation
Inventor: John DONOHUE , Phil WAGGONER , Scott PARKER , Wolfgang HINZ , Chiu Tai Andrew WONG
IPC: G01N33/487 , G01N27/02 , B01L3/00
CPC classification number: G01N33/48721 , B01L3/5085 , B01L2300/0645 , G01N27/021 , G01N27/028 , H03K17/6871
Abstract: A chemical sensor for analyte solutions utilizes AC excitation of a sample distributed in one or more micro-wells of a measurement device. The sensors utilize narrowband filtering of the measured signal(s), resulting in a large reduction in noise. Synchronous detection is utilized to provide high discrimination of the desired signal from noise or interfering sources. Conductance and by extension impedance is measured by applying a constant alternating current (AC) voltage across the electrodes of each micro-well and measuring the resulting current.
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公开(公告)号:US20160258011A1
公开(公告)日:2016-09-08
申请号:US15061273
申请日:2016-03-04
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Phil WAGGONER , James A. BALL , Wolfgang HINZ , Michael L. MINTO , Scott PARKER , David M. COX , Alexander MASTROIANNI , Jeremy GRAY , Marc GLAZER , Kimberly GORRELL
IPC: C12Q1/68 , G01N27/414
Abstract: A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.
Abstract translation: 传感器装置包括基板,设置在基板上的半导体器件,具有表面电极结构的半导体器件和形成在表面电极结构上的糖类涂层。 在使用前可以除去糖衣。 该半导体器件还可以包括一个阱以及可选地布置在阱中的珠。
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