公开(公告)号：US11162936B2

公开(公告)日：2021-11-02

申请号：US15595489

申请日：2017-05-15

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Daniel Young ,  Timothy Smith ,  Joy Roy ,  Alexander Loo

IPC: G01N33/00 ,  G01N21/00 ,  G01N33/50 ,  G01N21/07 ,  G01N35/00 ,  G01N21/51 ,  G01N21/76 ,  G01N30/88 ,  G01N21/64 ,  G01N15/10

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

公开(公告)号：US11385252B2

公开(公告)日：2022-07-12

申请号：US16541404

申请日：2019-08-15

Applicant: Labrador Diagnostics LLC

Inventor： Elizabeth A. Holmes ,  Timothy Smith ,  Alexander Loo ,  Daniel Young

IPC: G01N35/10 ,  G01N21/00 ,  G01N33/50 ,  G01N35/00

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

公开(公告)号：US20220056501A1

公开(公告)日：2022-02-24

申请号：US17361802

申请日：2021-06-29

Applicant: Labrador Diagnostics LLC

Inventor： Alexander Loo ,  Elizabeth A. Holmes

IPC: C12Q1/04 ,  B01F11/02 ,  G01N1/28 ,  G01N1/38 ,  G01N35/00

Abstract: Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.