EARLY CANCER BIOMARKER DETECTION USING COMBINED NANOPARTICLE-OPTICAL FIBRE, TUNABLE OPTICAL HETRODYNING, FLUORESCENCE AND SENSOR SYSTEM

    公开(公告)号:US20180348118A1

    公开(公告)日:2018-12-06

    申请号:US15996011

    申请日:2018-06-01

    Abstract: This invention relates a biomarker detection system, for detecting cancer biomarkers using optical heterodyning. The system includes a tunable laser configured to produce a plurality of laser beams of at least two frequencies, a pair of optical fibers coated with gold nanoparticles and functionalized with an antibody is configured to undergo a change of fiber surface of each optical fiber by adsorbing molecules of an analyte on a surface of the antibody, modify a reflection of the plurality of laser beams inside a fiber core of the each optical fiber when the each optical fiber is bent, and create an audible beat frequency; and perform spectral analysis. A frequency spectrum analyzer configured to provide a composition information of the adsorbed molecules based on a spectral analysis of the beat frequency.

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