公开(公告)号：US20230349893A1

公开(公告)日：2023-11-02

申请号：US18027587

申请日：2021-09-22

Applicant: McMaster University

Inventor： Tohid Didar ,  Amid Shakeri ,  Hanie Yousefi

IPC: G01N33/543

CPC classification number: G01N33/54353

Abstract: This application relates to a method for fabricating a biofunctionalized surface on a substrate, wherein the substrate comprises hydroxyl groups on the surface to be biofunctionalized, the method comprising: covalently attaching organosilane groups to less than all of the hydroxyl groups on the surface of the substrate; covalently attaching one or more biospecies to the surface of the substrate; and applying a lubricant to the substrate, wherein the biospecies comprises a biorecognition element that detects a target analyte in a sample. A biofunctionalized surface made therefrom and use thereof, such as for biosensing applications, are also disclosed.