LUBRICANT-INFUSED SURFACE BIOSENSING INTERFACE, METHODS OF MAKING AND USES THEREOF

    公开(公告)号:US20230349893A1

    公开(公告)日:2023-11-02

    申请号:US18027587

    申请日:2021-09-22

    CPC classification number: G01N33/54353

    Abstract: This application relates to a method for fabricating a biofunctionalized surface on a substrate, wherein the substrate comprises hydroxyl groups on the surface to be biofunctionalized, the method comprising: covalently attaching organosilane groups to less than all of the hydroxyl groups on the surface of the substrate; covalently attaching one or more biospecies to the surface of the substrate; and applying a lubricant to the substrate, wherein the biospecies comprises a biorecognition element that detects a target analyte in a sample. A biofunctionalized surface made therefrom and use thereof, such as for biosensing applications, are also disclosed.

    LUBRICANT-INFUSED MOLDS AND USES THEREOF
    6.
    发明申请

    公开(公告)号:US20200171713A1

    公开(公告)日:2020-06-04

    申请号:US16204165

    申请日:2018-11-29

    Abstract: The present application relates to lubricant-infused molds such as omniphobic lubricant-infused molds and uses thereof, for example, in processes for fabricating molded objects such as microfluidics devices. Such processes can comprise coating a mold with a layer comprising a lubricant-tethering group to obtain a tether-coated mold, depositing a lubricant on the tether-coated mold to obtain a lubricant-infused mold (LIM), depositing a molded object precursor into the LIM and solidifying to obtain the molded object, and removing the molded object from the LIM.

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