公开(公告)号：US20250102438A1

公开(公告)日：2025-03-27

申请号：US18897554

申请日：2024-09-26

Applicant: MediBeacon Inc.

Inventor： Jesse Ross-Jones ,  Jochen Friedemann

IPC: G01N21/64

Abstract: Method, system, and apparatus determines glomerular filtration rate (GFR) by obtaining a measurement data set. Furthermore, the disclosure includes obtaining a measurement data set comprising a plurality of measurement entries that are obtained before and after administration of an exogenous fluorescent agent; generating an intrinsic fluorescence (IF) signal representing a detected fluorescence intensity emitted by the exogenous fluorescent agent from within a diffuse reflecting medium; determining if the IF signal includes a portion of premature fluorescence data; identifying, upon determination of the portion of premature fluorescence data, an operable IF signal range by filtering the IF signal associated with premature fluorescence data; determining a GFR value in the patient based on a rate of change of the operable IF signal; providing the GFR value.