公开(公告)号：US09545584B2

公开(公告)日：2017-01-17

申请号：US14189619

申请日：2014-02-25

Applicant: NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY

Inventor： Constantine Y. Khripin ,  Ming Zheng

IPC: B01D11/02 ,  B01D15/02 ,  B01D17/02 ,  C01B31/02 ,  B03B5/00 ,  B82Y40/00

CPC classification number: B01D15/02 ,  B01D11/028 ,  B82Y40/00 ,  C01B32/172 ,  C01B2202/02 ,  C01B2202/22 ,  C01B2202/36

Abstract: A process for fractionating a nanoparticle composition, the process includes combining a first polymer, a second polymer, and a solvent to form a fluid and contacting the nanoparticle composition with the fluid. The nanoparticle composition includes a plurality of first nanoparticles, a plurality of second nanoparticles, and a dispersant disposed on an exterior surface of the first nanoparticles and the second nanoparticles. Fractionating the nanoparticle composition also includes forming a multiphase composition that includes a first phase and a second phase by partitioning the first polymer and the second polymer such that a concentration of the first polymer is greater than a concentration of the second polymer in the first phase, and the concentration of the second polymer is greater than the first polymer in the second phase, wherein the solvent is present in the first phase and the second phase. Additionally, the process includes apportioning the first nanoparticles and the second nanoparticles among the first phase and the second phase to fractionate the nanoparticle composition, based on a relative affinity of the first nanoparticles and the second nanoparticles for the first polymer and the second polymer, wherein the first nanoparticles are present in the first phase and substantially absent in the second phase, and the second nanoparticles are present in the second phase and substantially absent in the first phase.

Abstract translation: 一种用于分级纳米颗粒组合物的方法，该方法包括组合第一聚合物，第二聚合物和溶剂以形成流体并使纳米颗粒组合物与流体接触。 纳米颗粒组合物包括多个第一纳米颗粒，多个第二纳米颗粒和设置在第一纳米颗粒和第二纳米颗粒的外表面上的分散剂。 分级纳米颗粒组合物还包括通过分隔第一聚合物和第二聚合物形成包含第一相和第二相的多相组合物，使得第一聚合物的浓度大于第一相中第二聚合物的浓度， 并且第二聚合物的浓度大于第二相中的第一聚合物，其中溶剂存在于第一相和第二相中。 另外，该方法包括基于第一种纳米颗粒和第二种纳米颗粒对第一种聚合物和第二种聚合物的相对亲和力，在第一相和第二相中分配第一种纳米颗粒和第二种纳米颗粒以分级纳米颗粒组合物，其中 第一种纳米颗粒存在于第一相中，并且在第二相中基本上不存在，而第二种纳米颗粒存在于第二相中，并且在第一相中基本不存在。