公开(公告)号：US20240117293A1

公开(公告)日：2024-04-11

申请号：US18483882

申请日：2023-10-10

Applicant: NIRRIN TECHNOLOGIES, INC.

Inventor： Bryan A. Hassell ,  Gregory A. Phelps ,  David P. Marchessault

IPC: C12M1/00 ,  G01N21/27

CPC classification number: C12M41/06 ,  G01N21/274 ,  G01N2201/06113 ,  G01N2201/0683

Abstract: Devices for monitoring a bioreactor are configured for in-situ or ex-situ analysis. Noise from polarization dependent loss is addressed with a polarizer and reference photodetector for detecting a swept wavelength signal from a tunable laser spectrometer after transmission on a optical fiber but before a sample detection region.

公开(公告)号：US20230060089A1

公开(公告)日：2023-02-23

申请号：US17893279

申请日：2022-08-23

Applicant: Nirrin Technologies, Inc.

Inventor： Bryan A. Hassell ,  Gregory A. Phelps ,  David P. Marchessault

IPC: G01N15/14 ,  C12M1/34

Abstract: A method and system for studying cell viability and protein aggregation. In one aspect, the method relies on speckle information to analyze cells or other structures present in a fluid. A probe for measuring in situ structures includes a tip section having a sample detection region and a camera provided with image sensors.