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公开(公告)号：US20190212234A1
公开(公告)日：2019-07-11
申请号：US16310130
申请日：2017-06-16
Applicant: NanoCytomics, LLC , NORTHWESTERN UNIVERSITY
Inventor： Sergey Rozhok , Justin Derbas , Jarema Czarnecki , Hariharan Subramanian
Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
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公开(公告)号：US20160291045A1
公开(公告)日：2016-10-06
申请号：US15092153
申请日：2016-04-06
Applicant: Nanocytomics, LLC , Northwestern University
Inventor： Jarema Czarnecki , Justin Derbas , Sergey Rozhok , Hariharan Subramanian , Parvathi Viswanathan
CPC classification number: G01N35/00029 , G01N1/2813 , G01N1/312 , G01N35/00871 , G01N35/1011 , G01N2001/317 , G01N2035/00138 , G01N2035/00168 , G01N2035/00881
Abstract: Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
Abstract translation: 本文描述了能够自动喷雾沉积显微镜载玻片上的生物样品的系统和方法。 该技术的方面涉及例如自动化样品沉积系统和在自动化处理系统中产生高质量，可再现的载体显微镜载玻片的方法。
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公开(公告)号：US20220283192A1
公开(公告)日：2022-09-08
申请号：US17751127
申请日：2022-05-23
Applicant: NanoCytomics, LLC , Northwestern University
Inventor： Jarema Czarnecki , Justin Derbas , Sergey Rozhok , Hariharan Subramanian , Parvathi Viswanathan
Abstract: Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
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公开(公告)号：US20160331357A1
公开(公告)日：2016-11-17
申请号：US15156056
申请日：2016-05-16
Applicant: Nanocytomics, LLC , Northwestern University
Inventor： Jarema S. Czarnecki , Hariharan Subramanian , Yangrong (Elaine) Zhang , Vadim Backman , Hemant Roy
CPC classification number: A61B10/02 , A61B10/0291 , A61B10/04 , A61B42/10 , A61B42/20 , A61B90/37 , A61B2010/0216 , A61B2017/00438 , A61B2017/320004 , A61B2017/320012 , A61B2217/007
Abstract: A sample collection apparatus or device, various abrasive devices or components, and methods for their use, are provided for collecting samples from within a mammalian body. Tissue collection and sample preparation is the gold standard in cytology. Many cell scrapers and abrasives and their respective methods of collection destroy cellular tissue, decreasing the quality of the sample. Devices for obtaining cell and tissue samples, can comprise a collection device which is inserted into a cavity, a finger worn collection device, a glove based collection device and respective abrasive instruments or components.
Abstract translation: 用于从哺乳动物体内收集样品的样品收集装置或装置，各种研磨装置或部件及其使用方法。 组织采集和样品制备是细胞学的黄金标准。 许多细胞刮刀和磨料及其收集的方法破坏细胞组织，降低了样品的质量。 用于获得细胞和组织样本的装置可以包括插入空腔中的收集装置，手指磨损收集装置，基于手套的收集装置和相应的研磨器具或部件。
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公开(公告)号：US12158475B2
公开(公告)日：2024-12-03
申请号：US18164918
申请日：2023-02-06
Applicant: NanoCytomics, LLC , Northwestern University
Inventor： Jarema Czarnecki , Justin Derbas , Sergey Rozhok , Hariharan Subramanian , Parvathi Viswanathan
Abstract: Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems.
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Patent Agency Ranking
公开(公告)号：US20230288300A1
公开(公告)日：2023-09-14
申请号：US17958718
申请日：2022-10-03
Applicant: NanoCytomics, LLC , Northwestern University
Inventor： Sergey Rozhok , Justin R. Derbas , Jarema Czarnecki , Hariharan Subramanian
Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
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公开(公告)号：US09830501B2
公开(公告)日：2017-11-28
申请号：US14339239
申请日：2014-07-23
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Vadim Backman , Hariharan Subramanian , John E. Chandler , Craig White , Jeremy D. Rogers , Lusik Cherkezyan
IPC: G06K9/00 , G02B21/36 , H04N5/235 , H04N5/232 , G01J3/44 , G01J3/12 , G01J3/28 , G02B21/06 , G02B21/16 , G01N21/47
CPC classification number: G06K9/00127 , G01J3/1256 , G01J3/2823 , G01J3/44 , G01N21/47 , G01N2021/4709 , G02B21/06 , G02B21/16 , G02B21/365 , H04N5/23212 , H04N5/2354
Abstract: The present technology provides methods, systems, and apparatuses to achieve high throughput and high speed acquisition of partial wave spectroscopic (PWS) microscopic images. In particular, provided herein are high-throughput, automated partial wave spectroscopy (HT/A-PWS) instruments and systems capable of rapid acquisition of PWS Microscopic images and clinical, diagnostic, and research applications thereof.
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8.发明申请HIGH THROUGHPUT PARTIAL WAVE SPECTROSCOPIC MICROSCOPY AND ASSOCIATED SYSTEMS AND METHODS 有权高通量部分波光谱显微镜及相关系统及方法公开(公告)号：US20150029326A1
公开(公告)日：2015-01-29
申请号：US14339239
申请日：2014-07-23
Applicant: NORTHWESTERN UNIVERSITY
Inventor： Vadim Backman , Hariharan Subramanian , John E. Chandler , Craig White , Jeremy D. Rogers , Lusik Cherkezyan
CPC classification number: G06K9/00127 , G01J3/1256 , G01J3/2823 , G01J3/44 , G01N21/47 , G01N2021/4709 , G02B21/06 , G02B21/16 , G02B21/365 , H04N5/23212 , H04N5/2354
Abstract: The present technology provides methods, systems, and apparatuses to achieve high throughput and high speed acquisition of partial wave spectroscopic (PWS) microscopic images. In particular, provided herein are high-throughput, automated partial wave spectroscopy (HT/A-PWS) instruments and systems capable of rapid acquisition of PWS Microscopic images and clinical, diagnostic, and research applications thereof.
Abstract translation: 本技术提供方法，系统和设备，以实现部分波谱（PWS）显微镜图像的高吞吐量和高速采集。 特别地，本文提供了能够快速获取PWS显微镜图像及其临床，诊断和研究应用的高通量，自动部分波谱（HT / A-PWS）仪器和系统。
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公开(公告)号：US12066364B2
公开(公告)日：2024-08-20
申请号：US17958718
申请日：2022-10-03
Applicant: NanoCytomics, LLC , Northwestern University
Inventor： Sergey Rozhok , Justin R. Derbas , Jarema Czarnecki , Hariharan Subramanian
Abstract: Automated cell staining systems and methods are disclosed herein. In particular, the staining systems disclosed herein provide low-volume, automated bench top staining systems for staining biological samples contained on a cytological slide.
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公开(公告)号：US20240230689A9
公开(公告)日：2024-07-11
申请号：US18333828
申请日：2023-06-13
Applicant: NanoCytomics, LLC , Northwestern University
Inventor： Hariharan Subramanian , Michael Verleye , Micah Litow , Justin R. Derbas , Sergey Rozhok , John Hart , Chester Henderson , Rebecca Bartel , Nathan Ray , Anthony White
CPC classification number: G01N35/00029 , G01N1/2813 , G01N1/312 , G01N35/1002 , G01N2001/317 , G01N2035/00039
Abstract: Cell deposition and staining apparatuses and methods are disclosed herein. In particular, the deposition and staining apparatuses disclosed herein provide low-volume, automated bench top systems for depositing and staining cellular samples on a cytological slide. An example deposition and staining apparatus includes a housing having an access door; a substrate processing holder located within the housing configured to hold one or more substrates and/or one or more substrate cartridges, wherein the substrate processing holder is accessible when the access door is in an open configuration; at least one opening located at least partially above at least a portion of the substrate processing holder; a spray nozzle configured to dispense a gaseous substance into the substrate processing area; a user interface configured receive an input from a user, and in response to receiving the input, cause execution of a pre-programmed protocol; and a waste and/or reagent holder element.
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