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公开(公告)号：US10438576B2
公开(公告)日：2019-10-08
申请号：US15646759
申请日：2017-07-11
Applicant: Novartis AG
Inventor： Kirk Wellington Todd , Johan Gustaf Ekvall , Paul J. Essex , Steven T. Charles , Nicholas Max Gunn
IPC: G10K11/178 , A61F9/007 , A61B17/00
Abstract: Active noise cancellation is employed to address unwanted acoustical noise generated by various equipment associated with an ophthalmic surgical system. Active noise cancellation may be used within a chassis of the ophthalmic surgical system, within an air compressor used with the ophthalmic surgical system, and within a reciprocating surgical probe used with the ophthalmic surgical system.
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公开(公告)号：US20180018953A1
公开(公告)日：2018-01-18
申请号：US15646759
申请日：2017-07-11
Applicant: Novartis AG
Inventor： Kirk Wellington Todd , Johan Gustaf Ekvall , Paul J. Essex , Steven T. Charles , Nicholas Max Gunn
IPC: G10K11/178 , A61F9/007 , A61B17/00
CPC classification number: G10K11/178 , A61B2017/00544 , A61B2217/007 , A61F9/00763 , G10K11/17875 , G10K2210/109 , G10K2210/116 , G10K2210/3026
Abstract: Active noise cancellation is employed to address unwanted acoustical noise generated by various equipment associated with an ophthalmic surgical system. Active noise cancellation may be used within a chassis of the ophthalmic surgical system, within an air compressor used with the ophthalmic surgical system, and within a reciprocating surgical probe used with the ophthalmic surgical system.
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公开(公告)号：US20170119249A1
公开(公告)日：2017-05-04
申请号：US14925282
申请日：2015-10-28
Applicant: Novartis AG
Inventor： Nicholas Max Gunn
CPC classification number: A61B3/125 , A61F9/00736 , A61F9/009
Abstract: A lens holder for holding a vitrectomy lens during a surgical procedure may include a support ring sized and shaped to receive a portion of the vitrectomy lens to provide visualization of a surgical site in an eye of the patient. The support ring may be configured to rest upon the eye of the patient during a surgical treatment procedure performed on the eye. The lens holder may also include a transparent, flexible membrane disposed along a bottom plane of the support ring and configured to conform to a surface feature on the eye. It may also include an overflow trough to control contact of a wetting agent with the eye.
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公开(公告)号：US20180271643A1
公开(公告)日：2018-09-27
申请号：US15928311
申请日：2018-03-22
Applicant: Novartis AG
Inventor： Nicholas Max Gunn , Andrew David Johnson
CPC classification number: A61F2/14 , A61F9/0017 , A61F9/00781 , A61F2002/0081 , A61F2210/0004 , A61F2220/0008 , A61F2220/005 , A61F2230/0006 , A61L31/022 , A61L31/04 , A61L31/046 , A61L31/048 , A61L31/06 , A61L31/145 , A61L31/148 , A61L2430/16 , A61L2430/32
Abstract: Ophthalmic implants and methods of use that provide structural support to the optic nerve are disclosed herein. An adhesive and/or ophthalmic implant may be delivered to an optic nerve of an eye to relieve pressure on the optic nerve. The ophthalmic implant may include a base portion that includes a first surface and a second surface opposing the second surface and a protrusion from the second surface for extending into a cup of an optic nerve in an eye.
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公开(公告)号：US20170165109A1
公开(公告)日：2017-06-15
申请号：US15372691
申请日：2016-12-08
Applicant: Novartis AG
Inventor： Nicholas Max Gunn , Pooria Sharif Kashani , Michael J. Papac
CPC classification number: A61F9/0017 , A61B17/00491 , A61B17/0057 , A61B17/3468 , A61B2017/005 , A61B2017/00623 , A61B2017/00659 , A61F9/007 , A61F9/00727
Abstract: Systems, apparatuses, and methods of and for an ophthalmic surgical system are disclosed. In an exemplary implementation, an ophthalmic surgical system includes a patch sized and shaped to seal a retinal break of an eye by preventing fluid from infiltrating a sub-retinal space when adhered to the retina surrounding the retinal break; and a delivery device including a cannula configured to maintain the patch in a furled state for passage through an incision in the eye, the delivery device actuatable to deploy the patch within a vitreous chamber of the eye. In another exemplary implementation, an ophthalmic surgical method includes damaging tissue around a retinal break; delivering, into the vitreous chamber, a patch sized and shaped to seal the retinal break; positioning the patch on the retina surrounding the retinal break; and affixing the patch to the retina such that the patch prevents fluid from infiltrating a sub-retinal space.
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Patent Agency Ranking
公开(公告)号：US20150150720A1
公开(公告)日：2015-06-04
申请号：US14618102
申请日：2015-02-10
Applicant: NOVARTIS AG
Inventor： Nicholas Max Gunn , Andrew David Johnson
IPC: A61F9/007
CPC classification number: A61F9/00781 , A61F9/0017 , A61F2250/0003 , A61M2205/0244 , A61M2210/0612 , B81B2201/054 , B81B2203/0127 , F16K99/0015 , F16K99/0057 , F16K2099/0088 , Y10T137/7895
Abstract: A microfluidic valve for implantation in an eye of a patient is disclosed. The valve may include a chamber formed between a substrate and a flexible membrane. The valve may also include a boss disposed in the chamber and having a top edge in selective contact with the flexible membrane. The top edge includes a relief portion and a non-relief portion, with the relief portion being structurally arranged so that a pressure required to separate the membrane from the relief portion is less than a pressure required to separate the membrane from the non-relief portion. The valve also may include an inlet extending through the boss and the substrate through which fluid enters the chamber and an outlet configured to allow fluid to exit the chamber. Methods for priming a microfluidic valve are also disclosed.
Abstract translation: 公开了一种用于植入患者眼睛的微流体阀。 阀可以包括形成在基底和柔性膜之间的腔室。 阀还可以包括设置在腔室中并具有与柔性膜选择性接触的顶边缘的凸台。 顶部边缘包括一个浮雕部分和一个非浮雕部分，其中该浮雕部分在结构上被布置成使得隔离该浮雕部分所需的压力小于将膜与该非浮雕部分分开所需的压力 。 阀还可以包括延伸穿过凸台和基底的入口，流体通过该基底进入腔室，以及出口，其构造成允许流体离开腔室。 还公开了引发微流控阀的方法。
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公开(公告)号：US10667685B2
公开(公告)日：2020-06-02
申请号：US15833196
申请日：2017-12-06
Applicant: Novartis AG
Inventor： Grace C. Chang , Nicholas Max Gunn
Abstract: The present disclosure provides a small gauge extendable-retractable mirror for use in intraocular surgery. The mirror of the present disclosure can be used in intraocular surgery to enable visualization of areas of the eye currently difficult or impossible to view, such as, e.g., behind the iris.
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公开(公告)号：US10111777B2
公开(公告)日：2018-10-30
申请号：US14549356
申请日：2014-11-20
Applicant: Novartis AG
Inventor： Nicholas Max Gunn
IPC: A61F9/007 , A61B17/32 , A61B17/00 , A61B17/3207
Abstract: Apparatuses, systems, and methods are described for selectively generating an aspiration flow within a surgical instrument. Particularly, the disclosure describes example vitrectomy probes operable to selectively generate an aspiration flow in relation to operation of the cutter of the vitrectomy probe. In some instances, one or more valves may be used to form a barrier or closure and create a piston effect in order to selectively generate an aspiration flow.
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公开(公告)号：US09943226B2
公开(公告)日：2018-04-17
申请号：US14925282
申请日：2015-10-28
Applicant: Novartis AG
Inventor： Nicholas Max Gunn
CPC classification number: A61B3/125 , A61F9/00736 , A61F9/009
Abstract: A lens holder for holding a vitrectomy lens during a surgical procedure may include a support ring sized and shaped to receive a portion of the vitrectomy lens to provide visualization of a surgical site in an eye of the patient. The support ring may be configured to rest upon the eye of the patient during a surgical treatment procedure performed on the eye. The lens holder may also include a transparent, flexible membrane disposed along a bottom plane of the support ring and configured to conform to a surface feature on the eye. It may also include an overflow trough to control contact of a wetting agent with the eye.
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公开(公告)号：US09572712B2
公开(公告)日：2017-02-21
申请号：US14090192
申请日：2013-11-26
Applicant: Novartis AG
Inventor： Nicholas Max Gunn
CPC classification number: A61F9/00781 , A61N1/0428 , A61N1/0543
Abstract: An implantable fluidic valve actuated by osmotic pressure gradient and methods of operating it are provided. The valve includes: an input fluid channel; an output fluid channel in fluid communication with the input fluid channel at an aperture; and a semi-permeable membrane forming a portion of a sealed chamber. The semi-permeable membrane may have an outer surface forming a wall of the input fluid channel, and an inner surface forming a wall of the sealed chamber, the membrane being configured to allow diffusion of a solvent into and out of the sealed chamber; and a first electrode and a second electrode disposed within the sealed chamber configured to receive a voltage. A pump including the above elements and a check valve is provided. An ocular implant including an inlet tube sized to receive aqueous humor and an intra-ocular pressure control system having a fluidic valve as above is also provided.
Abstract translation: 提供了通过渗透压梯度驱动的可植入流体阀和操作它的方法。 该阀包括：输入流体通道; 在孔处与输入流体通道流体连通的输出流体通道; 以及形成密封室的一部分的半透膜。 半透膜可以具有形成输入流体通道的壁的外表面和形成密封室的壁的内表面，该膜被配置为允许溶剂扩散到密封室中并从密封室中流出; 以及设置在密封室内的第一电极和第二电极，被配置为接收电压。 提供包括上述元件和止回阀的泵。 还提供了一种眼部植入物，其包括尺寸适于接收房水的入口管和具有如上所述的流体阀的眼内压力控制系统。
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