公开(公告)号：US20170084024A1

公开(公告)日：2017-03-23

申请号：US15224088

申请日：2016-07-29

Applicant: Novadaq Technologies Inc.

Inventor： Lina GUREVICH

IPC: G06T7/00

CPC classification number: A61B5/0071 ,  A61B5/0261 ,  A61B5/0275 ,  A61B5/445 ,  A61B2576/02

Abstract: Methods and systems for assessing tissue of a subject include receiving a time series of signal intensity data capturing the transit of an imaging agent through tissue over a period of time, wherein the tissue comprises a plurality of calculation regions and wherein signal intensity in each calculation region over the period of time may be approximated by a time-intensity curve corresponding to the calculation region; determining, for each calculation region, a coefficient value that is related to at least a portion of the time-intensity curve corresponding to the calculation region; and converting the coefficient values across the plurality of calculation regions into a coefficient-derived image map.

公开(公告)号：US20160253800A1

公开(公告)日：2016-09-01

申请号：US15013945

申请日：2016-02-02

Applicant: Novadaq Technologies Inc.

Inventor： Lina GUREVICH ,  Jorgen WALLE-JENSEN

IPC: G06T7/00

CPC classification number: G06T7/0016 ,  A61B5/0071 ,  A61B5/445 ,  A61B6/486 ,  A61B6/507 ,  A61B6/5217 ,  A61B2576/02 ,  G06T2207/10064 ,  G06T2207/30088 ,  G06T2207/30096 ,  G06T2207/30104 ,  G06T2210/41 ,  G06T2211/404 ,  G16H50/50

Abstract: Methods and systems for characterizing tissue of a subject are disclosed. The method includes receiving a time series of fluorescence images of the tissue of the subject wherein the images define a plurality of calculation regions, generating a plurality of time-intensity curves for the plurality of calculation regions, creating a set of parameter values for each calculation region, generating a total rank value for each calculation region by comparing the sets of parameter values, and converting the total rank value into a ranking map image. Also disclosed are methods and systems for characterizing a wound in tissue by generating a wound index value.

Abstract translation: 公开了用于表征受试者组织的方法和系统。 该方法包括接收对象的组织的荧光图像的时间序列，其中图像限定多个计算区域，为多个计算区域生成多个时间 - 强度曲线，为每个计算创建一组参数值 区域，通过比较参数值的集合，并将总秩值转换为排名图图像来生成每个计算区域的总秩值。 还公开了通过产生伤口指数值来表征组织中伤口的方法和系统。

公开(公告)号：US20180028079A1

公开(公告)日：2018-02-01

申请号：US15663290

申请日：2017-07-28

Applicant: Novadaq Technologies Inc.

Inventor： Lina GUREVICH ,  Lori Ann SWALM

IPC: A61B5/0275 ,  G06K9/66 ,  G06T7/00 ,  G06K9/62 ,  A61B5/00 ,  A61B5/026

CPC classification number: A61B5/0275 ,  A61B5/0261 ,  A61B5/7232 ,  A61B5/7267 ,  A61B5/743 ,  A61B2576/00 ,  G06K9/6218 ,  G06K9/6219 ,  G06K9/6223 ,  G06K9/6274 ,  G06K9/66 ,  G06K2209/05 ,  G06T7/0012 ,  G06T7/557 ,  G06T2207/10024 ,  G06T2207/10064 ,  G06T2207/10081 ,  G06T2207/10104 ,  G06T2207/30024 ,  G06T2207/30104

Abstract: Methods and systems for characterizing tissue of a subject include acquiring and receiving data for a plurality of time series of fluorescence images, identifying one or more attributes of the data relevant to a clinical characterization of the tissue, and categorizing the data into clusters based on the attributes such that the data in the same cluster are more similar to each other than the data in different clusters, wherein the clusters characterize the tissue. The methods and systems further include receiving data for a subject time series of fluorescence images, associating a respective cluster with each of a plurality of subregions in the subject time series of fluorescence images, and generating a subject spatial map based on the clusters for the plurality of subregions in the subject time series of fluorescence images. The generated spatial maps may then be used as input for tissue diagnostics using supervised machine learning.

公开(公告)号：US20170124768A1

公开(公告)日：2017-05-04

申请号：US15337986

申请日：2016-10-28

Applicant: Novadaq Technologies Inc.

Inventor： Jorgen WALLE-JENSEN ,  Lina GUREVICH ,  Gregory Vincent BROWNE

IPC: G06T19/00 ,  A61K49/00 ,  G06T7/33

CPC classification number: G06T19/006 ,  A61B5/0071 ,  A61K49/0034 ,  G06T7/33 ,  G06T2207/10016 ,  G06T2207/10064 ,  G06T2207/30048 ,  G06T2207/30104 ,  G06T2207/30196 ,  G06T2207/30204 ,  G06T2210/41

Abstract: Methods and systems for alignment of a subject for medical imaging are disclosed, and involve providing a reference image of an anatomical region of the subject, the anatomical region comprising a target tissue, processing the reference image to generate an alignment reference image, displaying the alignment reference image concurrently with real-time video of the anatomical region, and aligning the real-time video with the alignment reference image to overlay the real-time video with the alignment reference image. Following such alignment, the subject may be imaged using, for example, fluorescence imaging, wherein the fluorescence imaging may be performed by an image acquisition assembly aligned in accordance with the alignment.