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Patent Agency Ranking
公开(公告)号：US10552945B2
公开(公告)日：2020-02-04
申请号：US14728396
申请日：2015-06-02
Applicant: OLYMPUS CORPORATION
Inventor： Hisao Kitagawa , Yusuke Yamashita , Yasunari Matsukawa
Abstract: A sample observation apparatus includes a memory and a main controller. The main controller stores a first number of photoelectrons required in a raw image for generating a super-resolution image. The main controller calculates the number of image data sets to be added together for generating the raw image based on the first number of photoelectrons stored in the memory and a predetermined image acquisition condition, acquires multiple sets of image data of the same region of a sample by repeatedly detecting light from the same region based on the calculated number of image data sets, and generates the raw image by adding together the acquired multiple sets of image data of the same region.
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公开(公告)号：US09733461B2
公开(公告)日：2017-08-15
申请号：US14580133
申请日：2014-12-22
Applicant: OLYMPUS CORPORATION
Inventor： Yasunari Matsukawa
CPC classification number: G02B21/0032 , G01N21/6458 , G01N2021/6471 , G01N2201/0675 , G02B21/0076 , G02B21/16
Abstract: To avoid unstable light radiation during switching of a phase modulation amount and stimulate desired stimulation points simultaneously, provided is a photo-stimulator which includes an AOM switching on/off of radiation of stimulation light to a specimen S; an LCOS-SLM being capable of modulating a phase of stimulation light once radiation to the specimen S has been turned on by the AOM; and a controller controlling the LCOS-SLM to switch a phase modulation amount of stimulation light and controlling the AOM to switch on/off of radiation of stimulation light, wherein the controller causes the AOM to turn off radiation of stimulation light before the LCOS-SLM starts switching a phase modulation amount, and causes the AOM to turn on radiation of stimulation light after the LCOS-SLM completes switching a phase modulation amount.
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3.发明授权公开(公告)号：US10473909B2
公开(公告)日：2019-11-12
申请号：US15861333
申请日：2018-01-03
Applicant: OLYMPUS CORPORATION
Inventor： Hiroyuki Yabugaki , Yasunari Matsukawa , Tetsuya Shirota
Abstract: A microscope system includes: an microscope provided with electronic units; a display configured to display operation information; a touch panel configured to detect a position of contact of an object from outside; a setting unit configured to set areas corresponding respectively to multiple operation functions in a detection area of the touch panel; a pressure detector configured to detect a value of a pressure applied in the position of contact; and a drive controller configured to generate, based on the position of contact that is detected by the touch panel, the number of positions of contact, a change of the position of contact over time, and the value of the pressure detected by the pressure detector, an instruction signal of an instruction to change an observation status in which the specimen is observed with the electronic unit corresponding to operation function that is set by the setting unit.
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公开(公告)号：US09625696B2
公开(公告)日：2017-04-18
申请号：US14880466
申请日：2015-10-12
Applicant: OLYMPUS CORPORATION
Inventor： Katsuyuki Hashimoto , Kunihiko Sasaki , Yasunari Matsukawa , Akinori Araya
CPC classification number: G02B21/365 , G02B21/002 , G02B21/0076 , G02B21/008 , G02B21/06 , G02B21/16
Abstract: A laser scanning microscope includes a light irradiating portion that irradiates a sample; a PMT that detects fluorescence from the sample and outputs an intensity signal; a data processing portion that converts the intensity signal to brightness information at each pixel; a full-scale setting portion that can set a normal full scale that is smaller than the intensity signal when a light stimulus is given and an expanded full scale that is larger than the normal full scale, as a maximum range of the intensity signal that can be converted to brightness information; and a control portion that determines whether to switch between a normal observation mode and a stimulation observation mode; wherein the full-scale switching portion sets the normal full scale in the normal observation mode and sets the expanded full scale in the stimulation observation mode.
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公开(公告)号：US09575002B2
公开(公告)日：2017-02-21
申请号：US14549283
申请日：2014-11-20
Applicant: OLYMPUS CORPORATION
Inventor： Yasunari Matsukawa
CPC classification number: G01N21/6428 , G02B21/0032 , G02B21/0076 , G02B2207/114
Abstract: The number of stimulated spots and/or the area of a stimulated spot is easily increased or decreased while keeping the irradiation power for each stimulated spot constant. Provided is a light stimulation device (3) that includes an objective lens (23) that radiates stimulation light emitted from a stimulation laser (11) onto a specimen (S); an LCOS-SLM (17) that is located at a position conjugate to the pupil of the objective lens (23) and that can modulate the phase of stimulation light to be made to enter the objective lens (23) based on a predetermined pupil modulation pattern; an AOM (13) that adjusts the amount of stimulation light to be made to enter the LCOS-SLM (17); a mouse (26) that is used to specify the number of spots and the position of a spot of light to be radiated onto the specimen (S); and a controller main unit (28) that determines the pupil modulation pattern for the LCOS-SLM (17) according to the number of spots and the position of a spot specified by means of the mouse (26) and that controls the AOM (13) such that, when the number of spots specified by means of the mouse (26) is changed, the amount of light to be radiated onto each spot before and after the change in the number of spots becomes constant.
Abstract translation: 刺激斑点的数量和/或刺激斑点的面积容易增加或减少，同时保持每个受激点的照射功率恒定。 提供了一种光刺激装置（3），其包括将从刺激激光器（11）发射的刺激光辐射到样本（S）上的物镜（23）; 位于与所述物镜（23）的光瞳共轭的位置的LCOS-SLM（17），并且能够基于预定的光瞳调制来调制待进入所述物镜（23）的刺激光的相位 模式; 调节进入LCOS-SLM（17）的刺激光量的AOM（13）; 用于指定要照射到样本（S）上的光点数和位置的鼠标（26）; 以及控制器主单元（28），其根据点数的数量和通过鼠标（26）指定的点的位置来确定LCOS-SLM（17）的光瞳调制模式，并且控制AOM（13 ），使得当通过鼠标（26）指定的点的数量改变时，要在点数变化之前和之后辐射到每个点上的光量变为恒定。
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