公开(公告)号：US20240344134A1

公开(公告)日：2024-10-17

申请号：US18292652

申请日：2022-07-26

Applicant: OSAKA UNIVERSITY

Inventor： Hayato HIKITA ,  Yuta MYOJIN ,  Tetsuo TAKEHARA

IPC: C12Q1/6886 ,  G01N33/574

CPC classification number: C12Q1/6886 ,  G01N33/57438 ,  C12Q2600/158

Abstract: The method of the present invention for evaluating the risk of developing liver cancer in a subject includes (1) a step of measuring a GDF15 level of a subject and (2) a step of relating the GDF15 level to the risk of developing liver cancer. When the GDF15 level measured in step (1) is not less than a cutoff value set in advance, the GDF15 level becomes an indicator that the subject has a high risk of developing liver cancer, and when the GDF15 level is less than the cutoff value, it becomes an indicator that the risk of developing liver cancer is low. The present invention also provides a kit for measuring GDF15 levels in a subject for use in the method of the present invention, and a diagnostic agent for evaluating the risk of developing liver cancer in a subject, which contains an anti-GDF15-specific antibody.