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公开(公告)号：US20220317014A1
公开(公告)日：2022-10-06
申请号：US17710244
申请日：2022-03-31
Applicant: OndaVia, Inc.
Inventor： Mark Charles PETERMAN , Merwan BENHABIB
Abstract: An analyte in water is quantified by mixing an internal standard with a water sample. The sample is analyzed with a Raman spectrometer. The analysis includes mapping the signal from the Raman spectrometer to the quantity of said analyte. The mapping can include using a calibration curve, for example a multivariate calibration curve, that was previously prepared with the internal standard. In other examples, a sample is measured after addition of a known amount of the analyte.
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公开(公告)号：US20170045453A1
公开(公告)日：2017-02-16
申请号：US15239153
申请日：2016-08-17
Applicant: OndaVia, Inc.
Inventor： Mark C. PETERMAN , Merwan BENHABIB , Samuel KLEINMAN
CPC classification number: G01N21/65 , B01L3/502761 , B01L2200/0652 , B01L2200/12 , B01L2300/0627 , B01L2300/0636 , B01L2300/0654 , B01L2300/0681 , B01L2300/0867 , B01L2300/087 , B01L2400/0418 , B01L2400/0421 , G01J3/18 , G01J3/44 , G01N21/47 , G01N21/4785 , G01N21/658 , G01N27/44704 , G01N27/44791 , G01N30/6065 , G01N30/6095 , G01N33/18 , G01N2021/651 , G01N2030/0095 , G01N2201/0221 , G01N2201/13
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge.
Abstract translation: 提供了一种手持微流体测试装置，其包括具有盒接收端口的壳体，用于输入到具有样品输入和通道的盒接收端口的盒，其中该通道包括拉曼散射纳米颗粒的混合物和校准 解决方案，其中校准溶液包括能够与待测试输入的样品与拉曼散射纳米颗粒相互作用的化合物和壳体中的光学检测系统，其中光学检测系统能够提供照明电场 ，其中照明电场能够用于具有拉曼散射纳米颗粒的拉曼光谱和校准溶液以分析被测试的输入到盒的样品。
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Patent Agency Ranking
3.发明申请公开(公告)号：US20210164955A1
公开(公告)日：2021-06-03
申请号：US17118482
申请日：2020-12-10
Applicant: OndaVia, Inc.
Inventor： Mark Charles PETERMAN , Merwan BENHABIB , Carlos Atico ARIZA , Samuel Louis KLEINMAN
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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4.发明申请公开(公告)号：US20200271634A1
公开(公告)日：2020-08-27
申请号：US16870530
申请日：2020-05-08
Applicant: OndaVia, Inc.
Inventor： Mark Charles PETERMAN , Merwan BENHABIB , Carlos Atico ARIZA , Samuel Louis KLEINMAN
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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5.发明申请公开(公告)号：US20200003744A1
公开(公告)日：2020-01-02
申请号：US16560579
申请日：2019-09-04
Applicant: OndaVia, Inc.
Inventor： Mark Charles PETERMAN , Merwan BENHABIB , Carlos Atico ARIZA , Samuel Louis KLEINMAN
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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6.发明申请公开(公告)号：US20180095062A1
公开(公告)日：2018-04-05
申请号：US15821098
申请日：2017-11-22
Applicant: OndaVia, Inc.
Inventor： Mark Charles PETERMAN , Merwan BENHABIB , Carlos Atico ARIZA , Samuel Louis KLEINMAN
CPC classification number: G01N33/18 , G01N21/658 , G01N33/182
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
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7.发明申请MEASURING CONCENTRATION OF ANALYTES IN LIQUID SAMPLES USING SURFACE-ENHANCED RAMAN SPECTROSCOPY 有权使用表面增强拉曼光谱测量液体样品中分析物的浓度公开(公告)号：US20170074799A1
公开(公告)日：2017-03-16
申请号：US15267708
申请日：2016-09-16
Applicant: ONDAVIA, INC.
Inventor： Mark Charles PETERMAN , Merwan BENHABIB , Carlos Atico ARIZA , Samuel Louis KLEINMAN
CPC classification number: G01N33/18 , G01N21/658 , G01N33/182
Abstract: A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port and a cartridge for input to the cartridge receiving port. An optical detection system in the housing is capable of providing an illuminated electric field useful for Raman spectroscopy. The cartridge may have a sample well. The sample well is loaded with a mixture of water containing the analyte, Raman-scattering nanoparticles and a calibration solution. The calibration solution contains an analogue of the analyte differing in its Raman response, for example an isotope of the analyte. Optionally, a chemical compound capable of increasing interaction between the analyte and the nanoparticles may be added.
Abstract translation: 提供了一种手持微流体测试装置，其包括具有盒接收端口和用于输入到盒接收端口的盒的壳体。 壳体中的光学检测系统能够提供用于拉曼光谱的照明电场。 墨盒可能有一个样品井。 样品孔装载含有分析物的水的混合物，拉曼散射纳米颗粒和校准溶液。 校准溶液含有其拉曼响应不同的分析物的类似物，例如分析物的同位素。 任选地，可以加入能够增加分析物和纳米颗粒之间的相互作用的化合物。
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