公开(公告)号：US11006825B2

公开(公告)日：2021-05-18

申请号：US16265840

申请日：2019-02-01

Applicant: OPTOVUE, INC.

Inventor： Jay Wei ,  Tony H. Ko ,  Yi-Sing Hsiao ,  Ben Jang ,  Richard Rosen

IPC: A61B3/12 ,  A61B3/10 ,  A61B3/00 ,  G06T7/00 ,  G06T7/12

Abstract: Optical Coherence Tomography Angiography (OCTA) image representation is obtained having OCTA pixels assigned respective OCTA values. A vessel density map is computed from the OCTA image representation. A fractional deviation map and/or a pattern deviation map is computed for the patient from the vessel density map and a normative database, wherein: (1) the fractional deviation map represents a percent loss of vessel density at each pixel location relative to an expected value based on the normative database; and (2) computing the pattern deviation map includes: computing a pattern map of the vessel density representing a normalized vessel density pattern of the vessel density map relative to an average value of the vessel density map; and computing the pattern deviation map using the pattern map. A loss is determined by using at least one of the fractional deviation map and the pattern deviation map. Other features are also provided.

公开(公告)号：US20190167099A1

公开(公告)日：2019-06-06

申请号：US16265840

申请日：2019-02-01

Applicant: OPTOVUE, INC.

Inventor： Jay Wei ,  Tony H. Ko ,  Yi-Sing Hsiao ,  Ben Jang ,  Richard Rosen

IPC: A61B3/12 ,  A61B3/10 ,  A61B3/00 ,  G06T7/12 ,  G06T7/00

Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.

公开(公告)号：US09492078B2

公开(公告)日：2016-11-15

申请号：US14101253

申请日：2013-12-09

Applicant: Optovue, Inc.

Inventor： Tony H. Ko ,  Yonghua Zhao ,  David Huang

IPC: G01B9/02 ,  A61B3/10 ,  A61B5/00 ,  A61B3/00

CPC classification number: A61B3/102 ,  A61B3/0025 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/7257 ,  G01B9/02004 ,  G01B9/0201 ,  G01B9/02021 ,  G01B9/02028 ,  G01B9/02044 ,  G01B9/02091

Abstract: An imager that can provide separated images corresponding to differing depths in a sample is presented. In accordance with some embodiments of the invention, an imager can include a light source; a sample arm that receives light from the light source, directs the light to a sample, and captures light returning from the sample; a modulation source that provides different modulations corresponding to differing imaging depths in the sample; a detector system to receive the captured light from the sample with the different modulations; and a processor that receives signals from the detector system and separates a plurality of images corresponding with the differing image depths in the sample.

公开(公告)号：US10258231B2

公开(公告)日：2019-04-16

申请号：US14985197

申请日：2015-12-30

Applicant: OPTOVUE, INC.

Inventor： Jay Wei ,  Tony H. Ko ,  Yi-Sing Hsiao ,  Ben Jang ,  Richard Rosen

IPC: A61B3/12 ,  A61B3/10 ,  A61B3/00 ,  G06T7/00 ,  G06T7/12

Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.

公开(公告)号：US10194866B2

公开(公告)日：2019-02-05

申请号：US15436704

申请日：2017-02-17

Applicant: OPTOVUE, INC.

Inventor： Yi-Sing Hsiao ,  Ben K. Jang ,  Utkarsh Sharma ,  Qienyuan Zhou ,  Tony H. Ko ,  Jay Wei

IPC: G06K9/00 ,  A61B5/00 ,  A61B3/00 ,  A61B3/10 ,  A61B3/12 ,  G06K9/46 ,  G06T7/00 ,  A61B5/02 ,  G06K9/40 ,  G06T5/00 ,  A61B6/00 ,  A61B5/026

Abstract: In some embodiments of the present invention, a method of reducing artifacts includes obtaining OCT/OCTA data from an OCT/OCTA imager; preprocessing OCTA/OCT volume data; extracting features from the preprocessed OCTA/OCT volume data; classifying the OCTA/OCT volume data to provide a probability determination data; determining a percentage data from the probability data determination; and reducing artifacts in response to the percentage data.

公开(公告)号：US20160183786A1

公开(公告)日：2016-06-30

申请号：US14985197

申请日：2015-12-30

Applicant: OPTOVUE, INC.

Inventor： Jay Wei ,  Tony H. Ko ,  Yi-Sing Hsiao ,  Ben Jang ,  Richard Rosen

IPC: A61B3/12 ,  A61B3/00 ,  A61B3/10

CPC classification number: A61B3/1233 ,  A61B3/0025 ,  A61B3/0041 ,  A61B3/102 ,  G06T7/0014 ,  G06T7/12 ,  G06T2200/24 ,  G06T2207/10101 ,  G06T2207/20044 ,  G06T2207/30041 ,  G06T2207/30104 ,  G06T2207/30172

Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.

Abstract translation: 存在处理3D OCT数据集的方法。 根据本发明的一些实施例的方法包括从3D OCT数据集获得OCT数据; 从3D OCT数据集获取OCTA数据; 对OCT数据中的至少一个边界执行分割; 在感兴趣区域中处理OCTA数据以通过向每个图像表示的每个像素分配值来创建至少一个图像表示; 并显示至少一个图像表示。