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公开(公告)号：US10571397B2
公开(公告)日：2020-02-25
申请号：US16116248
申请日：2018-08-29
Applicant: PHARMACOPHOTONICS, INC.
Inventor： Ruben Sandoval, Jr. , Erinn Reilly , Daniel Meier
Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
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Patent Agency Ranking
2.发明申请COMPOSITIONS AND METHODS FOR OPTIMIZING THE DETECTION OF FLUORESCENT SIGNALS FROM BIOMARKERS 审中-公开用于优化从生物标志物检测荧光信号的组合物和方法公开(公告)号：US20160266042A1
公开(公告)日：2016-09-15
申请号：US15031452
申请日：2014-10-24
Inventor： Ruben Sandoval, Jr. , Erinn Sheridan , Daniel Meier
CPC classification number: G01N21/6428 , A61K49/0041 , A61K49/0054 , A61M5/007 , G01N2021/6417 , G01N2021/6439 , G01N2201/13
Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
Abstract translation: 描述了用于增加由生物标志物产生的荧光信号的组合物和方法。 这用于当生物标志物用于检测和诊断生理条件（例如器官功能和血浆体积）时提高结果的准确性。
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公开(公告)号：US10279052B2
公开(公告)日：2019-05-07
申请号：US15116650
申请日：2015-02-06
Applicant: PharmacoPhotonics, Inc.
Inventor： Ruben Sandoval, Jr. , Erinn Sheridan Reilly , Daniel Meier
Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard umodified protein, colloid or crystalloid and a fluorescently-labeled protein colloid or crystalloid of approximately the same molecular weight. The use of blood volume expander to measure, adjust and maintain the level of blood volume in a patient also is described.
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公开(公告)号：US10994030B2
公开(公告)日：2021-05-04
申请号：US16363068
申请日：2019-03-25
Applicant: PharmacoPhotonics, Inc.
Inventor： Ruben Sandoval, Jr. , Erinn Sheridan Reilly , Daniel Meier
Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard unmodified protein, colloid or crystalloid and a fluorescently-labeled protein, colloid or crystalloid of approximately the same molecular weight. The use of blood volume expanders to measure, adjust and maintain the level of blood volume in a patient also is described.
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公开(公告)号：US10082465B2
公开(公告)日：2018-09-25
申请号：US15031452
申请日：2014-10-24
Applicant: PHARMACOPHOTONICS, INC.
Inventor： Ruben Sandoval, Jr. , Erinn Reilly , Daniel Meier
CPC classification number: G01N21/6428 , A61K49/0041 , A61K49/0054 , A61M5/007 , G01N2021/6417 , G01N2021/6439 , G01N2201/13
Abstract: Compositions and methods for increasing fluorescent signals generated by biomarkers are described. This serves to increase the accuracy of results when the biomarkers are used for the detection and diagnosis of physiological conditions, such as organ function and plasma volume.
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公开(公告)号：US20160346407A1
公开(公告)日：2016-12-01
申请号：US15116650
申请日：2015-02-06
Inventor： Ruben Sandoval, Jr. , Erinn Sheridan Reilly , Daniel Meier
IPC: A61K49/00 , G01N33/49 , A61K9/00 , A61K38/38 , A61K31/721
CPC classification number: A61K49/0043 , A61K9/0026 , A61K31/00 , A61K31/721 , A61K38/38 , A61K49/0041 , A61K49/0054 , A61K49/0056 , G01N33/49
Abstract: A method for measuring, adjusting and maintaining the level of blood volume in a patient is described. A blood volume expander composition includes, in combination, a standard umodified protein, colloid or crystalloid and a fluorescently-labeled protein colloid or crystalloid of approximately the same molecular weight. The use of blood volume expander to measure, adjust and maintain the level of blood volume in a patient also is described.
Abstract translation: 描述了用于测量，调节和维持患者体内血容量的方法。 血容积扩张剂组合物包含标准变质蛋白，胶体或晶体，以及具有大致相同分子量的荧光标记的蛋白质胶体或晶体。 还描述了使用血容量扩张器来测量，调节和维持患者血容量的水平。
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