公开(公告)号：US12091693B2

公开(公告)日：2024-09-17

申请号：US17497085

申请日：2021-10-08

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Philip Stewart Low ,  Venkatesh Chelvam ,  Youngsoon Kim ,  Sumith A Kularatne

IPC: C12N9/48 ,  A61K31/454 ,  A61K31/4745 ,  A61K31/475 ,  A61K38/00 ,  A61K47/54 ,  A61K49/00 ,  A61K51/04 ,  C12N9/96

CPC classification number: C12N9/485 ,  A61K31/454 ,  A61K31/4745 ,  A61K31/475 ,  A61K47/542 ,  A61K49/0032 ,  A61K49/0052 ,  A61K51/0402 ,  A61K51/0497 ,  C12N9/96 ,  A61K38/00 ,  C12Y304/17021

Abstract: Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical compositions containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.