TARGETED ANTIMICROBIAL PHOTODYNAMIC THERAPY
    1.
    发明申请

    公开(公告)号:US20200289649A1

    公开(公告)日:2020-09-17

    申请号:US16886927

    申请日:2020-05-29

    Abstract: The present application relates generally to a method and a composition matter that provides a rapid and potent antimicrobial photodynamic inactivation (aPDI) of pathogenic bacteria that express high-affinity cell-surface hemin receptors (CSHRs) using Ga(III)-protoporphyrins IX (GaPpIX or Ga-PpIX). The invention provides an effective treatment option for infections of skin or body cavities that are accessible to visible-light irradiation, such as a handheld LED array emitting visible light (405 nm), especially for infections caused by Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), pathogenic staphylococci, Streptococcus mutans, S. pneumoniae, S. pyogenes, streptococci, corynebacteria, mycobacteria, and Bacillus anthracis.

    TARGETED ANTIMICROBIAL PHOTODYNAMIC THERAPY
    2.
    发明申请

    公开(公告)号:US20190314502A1

    公开(公告)日:2019-10-17

    申请号:US16370153

    申请日:2019-03-29

    Abstract: The present application relates generally to a method and a composition matter that provides a rapid and potent antimicrobial photodynamic inactivation (aPDI) of pathogenic bacteria that express high-affinity cell-surface hemin receptors (CSHRs) using Ga(III)-protoporphyrins IX (GaPpIX or Ga-PpIX). The invention provides an effective treatment option for infections of skin or body cavities that are accessible to visible-light irradiation, such as a handheld LED array emitting visible light (405 nm), especially for infections caused by Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), pathogenic staphylococci, Streptococcus mutans, S. pneumoniae, S. pyogenes, streptococci, corynebacteria, mycobacteria, and Bacillus anthracis.

    Targeted antimicrobial photodynamic therapy

    公开(公告)号:US10722582B2

    公开(公告)日:2020-07-28

    申请号:US16370153

    申请日:2019-03-29

    Abstract: The present application relates generally to a method and a composition matter that provides a rapid and potent antimicrobial photodynamic inactivation (aPDI) of pathogenic bacteria that express high-affinity cell-surface hemin receptors (CSHRs) using Ga(III)-protoporphyrins IX (GaPpIX or Ga-PpIX). The invention provides an effective treatment option for infections of skin or body cavities that are accessible to visible-light irradiation, such as a handheld LED array emitting visible light (405 nm), especially for infections caused by Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), pathogenic staphylococci, Streptococcus mutans, S. pneumoniae, S. pyogenes, streptococci, corynebacteria, mycobacteria, and Bacillus anthracis.

    METHODS FOR SURFACTANT REMOVAL FROM NANOPARTICLE SUSPENSIONS
    9.
    发明申请
    METHODS FOR SURFACTANT REMOVAL FROM NANOPARTICLE SUSPENSIONS 审中-公开
    从纳米级悬浮液中除去表面活性剂的方法

    公开(公告)号:US20160051955A1

    公开(公告)日:2016-02-25

    申请号:US14830787

    申请日:2015-08-20

    CPC classification number: B01J13/0034 B01J13/0043 B01J13/0086 B82Y40/00

    Abstract: The present disclosure relates to the cleansing of nanoparticles in aqueous cationic surfactant solutions, including polyalkylammonium salts such as cetyltrimethylammonium bromide, as demonstrated by surfactant exchange, followed by the addition of peptizing agents to stabilize the cleansed nanoparticle solutes.

    Abstract translation: 本公开内容涉及在阳离子表面活性剂水溶液中清洁纳米颗粒,包括聚烷基铵盐如十六烷基三甲基溴化铵,如通过表面活性剂交换所证实的,然后加入胶溶剂以稳定清洁的纳米颗粒溶质。

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