Large scale production of catechol-containing polymers

    公开(公告)号:US12269908B2

    公开(公告)日:2025-04-08

    申请号:US17787190

    申请日:2020-12-17

    Abstract: This invention relates to a method for manufacturing a catechol-containing co-polymer through a suspension polymerization or a solution polymerization process. In some illustrative embodiments, this disclosure relates to a process of a free radical suspension polymerization for large-scale manufacturing catechol-containing copolymers. In some other illustrative embodiments, this disclosure relates to a solution polymerization of free radical, cationic, or anionic process for large-scale manufacturing catechol-containing copolymers. The process and the product thereof are within the scope of this disclosure.

    PROTEIN-BASED ADHESIVE AND ITS MODIFICATION

    公开(公告)号:US20210207013A1

    公开(公告)日:2021-07-08

    申请号:US17270095

    申请日:2019-08-22

    Abstract: This invention relates to protein-based adhesives that are capable to adhere to a substrate in a dry, wet, moist, or an aqueous environment. Particularly, said adhesives comprise a crosslinking agent and an elastin-like polypeptide (ELP) that contain tyrosine, lysine, cysteine, dihydroxyphenylalanine (DOPA) or trihydroxyphenylalanine (TOPA) amino acid residue, or a combination thereof, on the polypeptide chain of said ELP. Among others, the adhesives disclosed herein may find broad applications in medical treatments and surgical operations. Compositions and methods of use are within the scope of this application.

    PHOSPHATE-CONTAINING BIOMIMETIC POLYMERS AND USES THEREOF

    公开(公告)号:US20230303899A1

    公开(公告)日:2023-09-28

    申请号:US18023334

    申请日:2021-09-03

    CPC classification number: C09J143/02

    Abstract: This invention relates to a method for increasing wetting capability of a biomimetic polymer adhesive comprising the step of introducing plurality of phosphate moieties into said biomimetic polymer adhesive. In particular, the present disclosure relates a method to manufacture a biomimetic polymer adhesive with an increased wetting capability by inducing plurality of phosphate moieties by copolymerization of phosphate-containing monomer, such as monoacryloxyethyl phosphate (MAEP), together with other monomers, or by way of post-polymerization chemical derivertizations. The process and the product thereof are within the scope of this disclosure.

    LARGE SCALE PRODUCTION OF CATECHOL-CONTAINING POLYMERS

    公开(公告)号:US20230066557A1

    公开(公告)日:2023-03-02

    申请号:US17787190

    申请日:2020-12-17

    Abstract: This invention relates to a method for manufacturing a catechol-containing co-polymer through a suspension polymerization or a solution polymerization process. In some illustrative embodiments, this disclosure relates to a process of a free radical suspension polymerization for large-scale manufacturing catechol-containing copolymers. In some other illustrative embodiments, this disclosure relates to a solution polymerization of free radical, cationic, or anionic process for large-scale manufacturing catechol-containing copolymers. The process and the product thereof are within the scope of this disclosure.

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