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公开(公告)号：US20200249221A1
公开(公告)日：2020-08-06
申请号：US16851130
申请日：2020-04-17
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Pushpak Bhandari
IPC: G01N33/50 , A61K47/54 , A61K41/00 , A61K9/50 , A61P35/00 , G01N21/31 , A61M37/00 , A61K31/407 , A61K47/61 , A61K47/69 , A61K49/22
Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
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公开(公告)号：US20220146522A1
公开(公告)日：2022-05-12
申请号：US17502320
申请日：2021-10-15
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Wen Ren
IPC: G01N33/58 , B01L3/00 , G01N33/52 , G01N33/569 , G01N33/558
Abstract: The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.
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公开(公告)号：US09968692B2
公开(公告)日：2018-05-15
申请号：US14873208
申请日：2015-10-02
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Pushpak Bhandari
IPC: A61K49/22 , A61K31/337 , A61K33/00 , A61K41/00 , A61K9/51 , A61K9/00 , C12N15/115
CPC classification number: A61K49/223 , A61K9/0009 , A61K9/5161 , A61K31/337 , A61K33/00 , A61K41/0028 , C12N15/115 , C12N2310/16 , C12N2320/32 , A61K2300/00
Abstract: The present invention provides a nanobubble comprising a continuous outer shell, the outer shell comprising a cross-linked polymeric material, an inner wall of the continuous outer shell and a hollow core within the continuous outer shell. The nanobubble may be less than 250 nm in diameter. In a further aspect of the invention, the cross-linked polymeric material is a cellulose-based material.
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公开(公告)号：US20240337654A1
公开(公告)日：2024-10-10
申请号：US18749553
申请日：2024-06-20
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Wen Ren
IPC: G01N33/543 , B01L3/00 , G01N33/52 , G01N33/569 , G01N33/58
CPC classification number: G01N33/54388 , B01L3/5023 , G01N33/521 , G01N33/56916 , G01N33/586 , G01N33/587
Abstract: The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.
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Patent Agency Ranking
公开(公告)号：US11821892B2
公开(公告)日：2023-11-21
申请号：US16851130
申请日：2020-04-17
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Pushpak Bhandari
IPC: G01N33/50 , A61K49/22 , A61K47/69 , A61K47/61 , A61K31/407 , A61K41/00 , A61K9/50 , A61K47/54 , A61M37/00 , G01N21/31 , A61P35/00 , G01N21/64
CPC classification number: G01N33/5008 , A61K9/5047 , A61K31/407 , A61K41/00 , A61K41/0028 , A61K47/54 , A61K47/61 , A61K47/6925 , A61K49/223 , A61M37/0092 , A61P35/00 , G01N21/31 , A61M2210/1085 , G01N21/6428 , G01N21/6456 , G01N2021/6439
Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
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公开(公告)号：US12031983B2
公开(公告)日：2024-07-09
申请号：US17502320
申请日：2021-10-15
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Wen Ren
IPC: G01N33/543 , B01L3/00 , G01N33/52 , G01N33/569 , G01N33/58
CPC classification number: G01N33/54388 , B01L3/5023 , G01N33/521 , G01N33/56916 , G01N33/586 , G01N33/587
Abstract: The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens.
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公开(公告)号：US10670581B2
公开(公告)日：2020-06-02
申请号：US15914293
申请日：2018-03-07
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Pushpak Bhandari
IPC: A61K9/50 , A61K41/00 , A61K47/54 , A61K47/69 , A61K47/61 , A61K49/22 , G01N21/31 , G01N33/50 , A61K31/407 , A61M37/00 , A61P35/00 , G01N21/64
Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
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公开(公告)号：US20180252702A1
公开(公告)日：2018-09-06
申请号：US15914293
申请日：2018-03-07
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Pushpak Bhandari
IPC: G01N33/50 , A61K49/22 , A61K47/69 , A61K47/61 , A61K31/407 , A61K41/00 , A61P35/00 , A61M37/00 , G01N21/31 , G01N21/64
CPC classification number: G01N33/5008 , A61K9/5047 , A61K31/407 , A61K41/00 , A61K41/0028 , A61K47/54 , A61K47/61 , A61K47/6925 , A61K49/223 , A61M37/0092 , A61M2210/1085 , A61P35/00 , G01N21/31 , G01N21/6428 , G01N21/6456 , G01N2021/6439
Abstract: The present invention provides oxygenized nanobubbles and their uses in imaging and cancer treatment when combined with therapeutic drugs and precise ultrasound beam steering.
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公开(公告)号：US20160166716A1
公开(公告)日：2016-06-16
申请号：US14873208
申请日：2015-10-02
Applicant: Purdue Research Foundation
Inventor： Joseph Irudayaraj , Pushpak Bhandari
IPC: A61K49/22 , A61K33/00 , C12N15/115 , A61K31/337 , A61K9/16
CPC classification number: A61K49/223 , A61K9/0009 , A61K9/5161 , A61K31/337 , A61K33/00 , A61K41/0028 , C12N15/115 , C12N2310/16 , C12N2320/32 , A61K2300/00
Abstract: The present invention provides a nanobubble comprising a continuous outer shell, the outer shell comprising a cross-linked polymeric material, an inner wall of the continuous outer shell and a hollow core within the continuous outer shell. The nanobubble may be less than 250 nm in diameter. In a further aspect of the invention, the cross-linked polymeric material is a cellulose-based material.
Abstract translation: 本发明提供一种包含连续外壳的纳米气泡，所述外壳包括交联聚合材料，所述连续外壳的内壁和所述连续外壳内的中空芯。 纳米气泡的直径可以小于250nm。 在本发明的另一方面，交联聚合物材料是基于纤维素的材料。
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