公开(公告)号：US10335547B2

公开(公告)日：2019-07-02

申请号：US14349511

申请日：2012-10-24

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Matthew P. Ward ,  Pedro Irazoqui

IPC: A61B5/00 ,  A61B5/04 ,  A61N1/36 ,  A61N5/06 ,  A61N7/00 ,  A61M5/172

Abstract: The present disclosure is directed to a method and apparatus to autonomously stimulate a plurality of nerve fiber groups. The method and apparatus predicts stimulus parameters that can activate 0-100% of the nerve fiber groups selectively according to a patient's characteristics and proportional to therapeutic outcomes, such as determined by experimental data. The method and apparatus may further be configured to input experimental third-party data to obtain a high efficacy from a patient without invasive neurosurgery.

公开(公告)号：US12053425B2

公开(公告)日：2024-08-06

申请号：US16732064

申请日：2019-12-31

Applicant: Purdue Research Foundation

Inventor： Matthew P. Ward ,  Pedro P. Irazoqui ,  Muhammad Abdullah Arafat

IPC: A61H23/00 ,  A61B5/00 ,  A61B5/24 ,  A61F2/50 ,  A61H23/02 ,  A61N1/04 ,  A61N1/05 ,  H04L67/00 ,  H04L67/12 ,  A61F2/48 ,  A61N1/00

CPC classification number: A61H23/02 ,  A61B5/24 ,  A61B5/4836 ,  A61B5/4851 ,  A61B5/6811 ,  A61B5/7455 ,  A61H23/0218 ,  A61N1/0456 ,  A61N1/0551 ,  H04L67/00 ,  H04L67/12 ,  A61F2/482 ,  A61F2/50 ,  A61H2201/0207 ,  A61H2201/0214 ,  A61H2201/0285 ,  A61H2201/10 ,  A61H2201/5002 ,  A61H2201/5007 ,  A61H2201/5012 ,  A61H2201/5043 ,  A61H2201/5071 ,  A61H2201/5082 ,  A61H2205/027 ,  A61H2230/105 ,  A61N1/00

Abstract: High-resolution, selective, and self-optimizing haptic and electrotactile display and methods of use. In an embodiment of a feedback system referenced herein, the feedback system includes a prosthesis configured to be worn by an individual, including at least one prosthesis sensor configured to detect a state or condition in an environment of the at least one prosthesis sensor, and at least one actuator in communication with the at least one prosthesis sensor and configured to receive data relating to the detected state or condition and to stimulate a nerve of the individual; a neural sensor positioned upon or within the individual, configured to detect a neural response relating to the stimulation of the nerve by the at least one actuator; and a processor in communication with at least one of the at least one prosthesis sensor, at least one of the at least one actuator, and the neural sensor.

公开(公告)号：US20210260372A1

公开(公告)日：2021-08-26

申请号：US17128123

申请日：2020-12-20

Applicant: Purdue Research Foundation

Inventor： Matthew P. Ward

IPC: A61N1/36 ,  A61N1/372 ,  G16H20/30 ,  G16H50/80 ,  G16H40/67 ,  G16H10/20 ,  G16H50/70 ,  G16H50/20

Abstract: A gastric electric stimulation (GES) system is disclosed which includes a processing system, and at least one of a left vagus nerve sensor (L/R Sensors) and a right vagus nerve sensor coupled to the processing system, the processing system is configured to receive a model which statistically correlates sensed compound nerve action potential (CNAP) parameters measured from at least one of left and right vagus nerves of subjects within a population to feedback surveys of the subjects corresponding to a plurality of gastric symptoms and symptom parameters, receive one or more gastric symptoms of a subject outside of the population (Subjectout), determine CNAP parameters that correspond to the gastric symptoms with least severity (CNAPmin), measure CNAP activity of the Subjectout from the L/R sensors while modifying GES parameters for the Subjectout, select the GES parameters that corresponds to the CNAPmin (GESout), and output the GESout.

公开(公告)号：US20200345578A1

公开(公告)日：2020-11-05

申请号：US16732064

申请日：2019-12-31

Applicant: Purdue Research Foundation

Inventor： Matthew P. Ward ,  Pedro P. Irazoqui ,  Muhammad Abdullah Arafat

IPC: A61H23/02 ,  A61B5/04 ,  A61B5/00 ,  A61N1/04 ,  A61N1/05 ,  H04L29/08

Abstract: High-resolution, selective, and self-optimizing haptic and electrotactile display and methods of use. In an embodiment of a feedback system referenced herein, the feedback system includes a prosthesis configured to be worn by an individual, including at least one prosthesis sensor configured to detect a state or condition in an environment of the at least one prosthesis sensor, and at least one actuator in communication with the at least one prosthesis sensor and configured to receive data relating to the detected state or condition and to stimulate a nerve of the individual; a neural sensor positioned upon or within the individual, configured to detect a neural response relating to the stimulation of the nerve by the at least one actuator; and a processor in communication with at least one of the at least one prosthesis sensor, at least one of the at least one actuator, and the neural sensor.

公开(公告)号：US20160346164A1

公开(公告)日：2016-12-01

申请号：US15167527

申请日：2016-05-27

Applicant: Purdue Research Foundation

Inventor： Matthew P. Ward ,  Pedro P. Irazoqui ,  Muhammad Abdullah Arafat

IPC: A61H23/02 ,  A61B5/04 ,  A61B5/00 ,  A61F7/00

CPC classification number: A61H23/02 ,  A61B5/04001 ,  A61B5/04888 ,  A61B5/4836 ,  A61B5/4851 ,  A61B5/6811 ,  A61B5/7455 ,  A61H23/0218 ,  A61H2201/0207 ,  A61H2201/0214 ,  A61H2201/0285 ,  A61H2201/10 ,  A61H2201/5002 ,  A61H2201/5007 ,  A61H2201/5012 ,  A61H2201/5043 ,  A61H2201/5071 ,  A61H2201/5082 ,  A61H2205/027 ,  A61H2230/105 ,  A61N1/00 ,  A61N1/0456 ,  A61N1/0551 ,  H04L67/00 ,  H04L67/12

Abstract: High-resolution, selective, and self-optimizing haptic and electrotactile display and methods of use. In an embodiment of a feedback system referenced herein, the feedback system comprises a prosthesis configured to be worn by an individual, comprising at least one prosthesis sensor configured to detect a state or condition in an environment of the at least one prosthesis sensor, and at least one actuator in communication with the at least one prosthesis sensor and configured to receive data relating to the detected state or condition and to stimulate a nerve of the individual; a neural sensor positioned upon or within the individual, configured to detect a neural response relating to the stimulation of the nerve by the at least one actuator; and a processor in communication with at least one of the at least one prosthesis sensor, at least one of the at least one actuator, and the neural sensor.

Abstract translation: 高分辨率，选择性和自我优化的触觉和电泳显示和使用方法。 在这里引用的反馈系统的实施例中，反馈系统包括被配置为由个人佩戴的假体，包括至少一个假体传感器，其构造成检测至少一个假体传感器的环境中的状态或状况，以及在 至少一个致动器，其与所述至少一个假体传感器通信并且被配置为接收与所述检测到的状态或状况相关的数据并刺激所述个体的神经; 定位在个体上或内部的神经传感器，被配置为检测由至少一个致动器刺激神经的神经反应; 以及与所述至少一个假体传感器，所述至少一个致动器和所述神经传感器中的至少一个的至少一个通信的处理器。

公开(公告)号：US20140243714A1

公开(公告)日：2014-08-28

申请号：US14349511

申请日：2012-10-24

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Matthew P. Ward ,  Pedro Irazoqui

IPC: A61N1/36 ,  A61N7/00 ,  A61N5/06 ,  A61M5/172

CPC classification number: A61M5/1723 ,  A61B5/04 ,  A61B5/4035 ,  A61B5/4836 ,  A61N1/36053 ,  A61N1/36139 ,  A61N1/3615 ,  A61N1/36167 ,  A61N1/36171 ,  A61N1/36175 ,  A61N5/0622 ,  A61N7/00 ,  A61N2007/0026

Abstract: The present disclosure is directed to a method and apparatus to autonomously stimulate a plurality of nerve fiber groups. The method and apparatus predicts stimulus parameters that can activate 0-100% of the nerve fiber groups selectively according to a patient's characteristics and proportional to therapeutic outcomes, such as determined by experimental data. The method and apparatus may further be configured to input experimental third-party data to obtain a high efficacy from a patient without invasive neurosurgery.

Abstract translation: 本公开涉及一种自主刺激多个神经纤维组的方法和装置。 该方法和装置预测刺激参数，其可以根据患者的特征选择性地激活0-100％的神经纤维组，并且与治疗结果成比例，例如由实验数据确定。 所述方法和装置还可被配置为输入实验性第三方数据，以从没有侵入性神经外科学的患者获得高效力。

公开(公告)号：US11511111B2

公开(公告)日：2022-11-29

申请号：US17128123

申请日：2020-12-20

Applicant: Purdue Research Foundation

Inventor： Matthew P. Ward

IPC: A61N1/00 ,  A61N1/36 ,  G16H50/20 ,  G16H20/30 ,  G16H50/80 ,  G16H40/67 ,  G16H10/20 ,  G16H50/70 ,  A61N1/372

Abstract: A gastric electric stimulation (GES) system is disclosed which includes a processing system, and at least one of a left vagus nerve sensor (L/R Sensors) and a right vagus nerve sensor coupled to the processing system, the processing system is configured to receive a model which statistically correlates sensed compound nerve action potential (CNAP) parameters measured from at least one of left and right vagus nerves of subjects within a population to feedback surveys of the subjects corresponding to a plurality of gastric symptoms and symptom parameters, receive one or more gastric symptoms of a subject outside of the population (Subjectout), determine CNAP parameters that correspond to the gastric symptoms with least severity (CNAPmin), measure CNAP activity of the Subjectout from the L/R sensors while modifying GES parameters for the Subjectout, select the GES parameters that corresponds to the CNAPmin (GESout), and output the GESout.

公开(公告)号：US10517791B2

公开(公告)日：2019-12-31

申请号：US15167527

申请日：2016-05-27

Applicant: Purdue Research Foundation

Inventor： Matthew P. Ward ,  Pedro P. Irazoqui ,  Muhammad Abdullah Arafat

IPC: A61H23/00 ,  A61B5/00 ,  A61F7/00 ,  A61H23/02 ,  A61B5/04

Abstract: High-resolution, selective, and self-optimizing haptic and electrotactile display and methods of use. In an embodiment of a feedback system referenced herein, the feedback system includes a prosthesis configured to be worn by an individual, including at least one prosthesis sensor configured to detect a state or condition in an environment of the at least one prosthesis sensor, and at least one actuator in communication with the at least one prosthesis sensor and configured to receive data relating to the detected state or condition and to stimulate a nerve of the individual; a neural sensor positioned upon or within the individual, configured to detect a neural response relating to the stimulation of the nerve by the at least one actuator; and a processor in communication with at least one of the at least one prosthesis sensor, at least one of the at least one actuator, and the neural sensor.