公开(公告)号：US20240273677A1

公开(公告)日：2024-08-15

申请号：US18423669

申请日：2024-01-26

Applicant: Purdue Research Foundation

Inventor： Young L. KIM ,  Yuhyun JI ,  Sang Mok PARK ,  Semin KWEON ,  Jungwoo LEEM

IPC: G06T5/50 ,  G01N21/31 ,  G01N33/483 ,  G06T7/00 ,  H04N23/10

CPC classification number: G06T5/50 ,  G01N21/31 ,  G01N33/4833 ,  G06T7/0012 ,  H04N23/10 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/10056 ,  G06T2207/20081 ,  G06T2207/20084 ,  G06T2207/30024

Abstract: A method of generating an image or video of a field of interest of a sample which includes obtaining i) a first RGB image from a field of interest of a sample, and ii) hyperspectral data from a subarea of the field of interest, extracting an RGB image of the subarea from the first RGB image of the field of interest, applying the hyperspectral data of the subarea to conduct a spectroscopic analysis of a sample thereby generating spectral parameters, inputting i) the spectral parameters, and ii) the first RGB image, collectively as training input data to a deep learning model (DLM), training the DLM with the training input data thus generating a trained DLM, obtaining and inputting a second RGB image of about the field of interest to the trained DLM, and outputting from the trained DLM a spectral map for the field of interest.

公开(公告)号：US20140046196A1

公开(公告)日：2014-02-13

申请号：US13964722

申请日：2013-08-12

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： Young L. KIM ,  Raymond L. KONGER ,  Ally-Khan SOMANI ,  Zhengbin XU

IPC: A61B5/00

CPC classification number: A61B5/0075 ,  A61B5/02007

Abstract: An apparatus and method of mesoscopic imaging which provide improved contrast to changes in tumor microenvironments are disclosed. The apparatus includes a light which illuminates tissue in vivo, a spectrometer which varies at least one parameter of the light, and optics which transmit light backscattered from the tissue. The optics comprise any one of (i) a small aperture 4-focal length (4-f) lens system within an angular cone of 2°-5°, (ii) a telecentric lens, and (iii) an anti-scatter grid and a camera lens.

Abstract translation: 公开了一种提供与肿瘤微环境变化的对比度的介观成像装置和方法。 该装置包括在体内照射组织的光，改变光的至少一个参数的光谱仪和从组织反射散射光的光学器件。 光学元件包括（i）2°-5°的角锥内的小孔4-焦距（4-f）透镜系统，（ii）远心透镜，和（iii）防散射栅格 和相机镜头。