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公开(公告)号:US11674132B2
公开(公告)日:2023-06-13
申请号:US16997614
申请日:2020-08-19
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago
IPC: G01N27/453 , C12N15/10 , G01N27/447 , B01L3/00 , C12Q1/6806 , B81B1/00 , B81B7/00
CPC classification number: C12N15/101 , B01L3/502753 , C12N15/10 , C12Q1/6806 , G01N27/4473 , G01N27/44739 , G01N27/44791 , G01N27/44795 , B01L3/502738 , B01L2300/0627 , B01L2300/0867 , B81B1/004 , B81B7/0087 , B81B2201/0278 , B81B2201/05 , B81B2203/0338 , G01N27/44704 , C12N15/101 , C12Q2565/125
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US20240301395A1
公开(公告)日:2024-09-12
申请号:US18653435
申请日:2024-05-02
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago
IPC: C12N15/10 , B01L3/00 , B81B1/00 , B81B7/00 , C12Q1/6806 , G01N27/447
CPC classification number: C12N15/101 , B01L3/502753 , C12N15/10 , C12Q1/6806 , G01N27/4473 , G01N27/44739 , G01N27/44791 , G01N27/44795 , B01L3/502738 , B01L2300/0627 , B01L2300/0867 , B81B1/004 , B81B7/0087 , B81B2201/0278 , B81B2201/05 , B81B2203/0338 , G01N27/44704
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US12006496B2
公开(公告)日:2024-06-11
申请号:US18141641
申请日:2023-05-01
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago
IPC: G01N27/453 , B01L3/00 , C12N15/10 , C12Q1/6806 , G01N27/447 , B81B1/00 , B81B7/00
CPC classification number: C12N15/101 , B01L3/502753 , C12N15/10 , C12Q1/6806 , G01N27/4473 , G01N27/44739 , G01N27/44791 , G01N27/44795 , B01L3/502738 , B01L2300/0627 , B01L2300/0867 , B81B1/004 , B81B7/0087 , B81B2201/0278 , B81B2201/05 , B81B2203/0338 , G01N27/44704 , C12N15/101 , C12Q2565/125
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US20230416724A1
公开(公告)日:2023-12-28
申请号:US18212882
申请日:2023-06-22
Applicant: Purigen Biosystems, Inc.
Inventor: Nathan P. Hoverter , Lewis A. Marshall , Klint A. Rose , Debannita Datta , Douglas Fadrosh
IPC: C12N15/10 , G01N27/447
CPC classification number: C12N15/101 , G01N27/44721
Abstract: The present disclosure provides cell lysis buffers and method of use. Cell lysis buffers may comprise an aqueous solution comprising a buffering agent, a detergent, and cyanate or thiocyanate. The cell lysis buffers may be free or substantially free of urea and/or carbonic acid. Such lysis buffers may be used to lyse cells, e.g., in tissues. The cell lysis buffers may be suitable for use with isotachophoresis.
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公开(公告)号:US20230357748A1
公开(公告)日:2023-11-09
申请号:US18141641
申请日:2023-05-01
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago
IPC: C12N15/10 , G01N27/447 , B01L3/00 , C12Q1/6806
CPC classification number: C12N15/101 , G01N27/44791 , C12N15/10 , B01L3/502753 , C12Q1/6806 , G01N27/4473 , G01N27/44739 , G01N27/44795 , G01N27/44704 , B01L3/502738 , B01L2300/0627 , B01L2300/0867 , B81B1/004
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US10822603B2
公开(公告)日:2020-11-03
申请号:US16046560
申请日:2018-07-26
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago
IPC: G01N27/447 , C12N15/10 , B01L3/00 , C12Q1/6806 , B81B1/00 , B81B7/00
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US11987789B2
公开(公告)日:2024-05-21
申请号:US17230582
申请日:2021-04-14
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago , Matthew S. Munson , Janine Mok , Sean Arin , Yatian Qu , Andrew Lee , Michael Christopher De Renzi
IPC: B01L3/00 , B01L9/00 , C12N15/10 , G01N27/447
CPC classification number: C12N15/101 , B01L3/502738 , B01L3/502746 , B01L3/502761 , B01L3/502776 , B01L3/5085 , G01N27/44717 , B01L9/527 , B01L2200/0621 , B01L2200/0642 , B01L2400/0421 , B01L2400/0688 , G01N27/44704 , G01N27/44743 , G01N27/44791
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US20230383280A1
公开(公告)日:2023-11-30
申请号:US18231601
申请日:2023-08-08
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago , Matthew S. Munson , Janine Mok , Sean Arin , Yatian Qu , Andrew Lee , Michael Christopher De Renzi
IPC: C12N15/10 , B01L3/00 , G01N27/447
CPC classification number: C12N15/101 , B01L3/502738 , B01L3/502746 , B01L3/502761 , B01L3/502776 , B01L3/5085 , G01N27/44717 , B01L2200/0621 , B01L9/527
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US11041150B2
公开(公告)日:2021-06-22
申请号:US16052565
申请日:2018-08-01
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago , Matthew S. Munson , Janine Mok , Sean Arin , Yatian Qu , Andrew Lee , Michael Christopher DeRenzi
IPC: B01L3/00 , G01N27/447 , C12N15/10 , B01L9/00
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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公开(公告)号:US10415030B2
公开(公告)日:2019-09-17
申请号:US16175500
申请日:2018-10-30
Applicant: Purigen Biosystems, Inc.
Inventor: Lewis A. Marshall , Amy L. Hiddessen , Nathan P. Hoverter , Klint A. Rose , Juan G. Santiago
IPC: C12N15/10 , G01N27/447 , B01L3/00 , C12Q1/6806 , B81B1/00 , B81B7/00
Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.
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