公开(公告)号：US12296189B2

公开(公告)日：2025-05-13

申请号：US17907546

申请日：2021-03-22

Applicant: RaySearch Laboratories AB (Publ)

Inventor： Bjorn Andersson ,  Erik Engwall ,  Albin Fredriksson ,  Kjell Eriksson

IPC: A61N5/10

Abstract: A computer-based method of optimizing a radiotherapy treatment plan for a patient is proposed, wherein a complete treatment comprising both external beam therapy and brachytherapy is optimized in one procedure using an optimization problem comprising an objective function designed to optimize the total dose distribution as a combination of a first dose distribution to be provided by a first radiation set and a second dose distribution to be provided by a second radiation set. One of the radiation sets is external beam radiotherapy and the other is brachytherapy. The optimization is based on a total desired dose for the whole treatment, images of the patient before the treatment starts and an estimated image of the patient after the first radiation set has been delivered.

公开(公告)号：US11992704B2

公开(公告)日：2024-05-28

申请号：US17596506

申请日：2020-06-02

Applicant: RaySearch Laboratories AB

Inventor： Bjorn Andersson ,  Cecilia Battinelli ,  Rasmus Bokrantz

IPC: A61N5/10

CPC classification number: A61N5/1031 ,  A61N2005/1087

Abstract: A method of radiotherapy treatment planning for particle-based arc treatment comprises the steps of



determining (S11; S21) an initial set of candidate energy layers,
performing a calculation on the initial set,
determining (S13; S23), based on the outcome of said calculation, at least one additional energy layer to produce an expanded candidate layer set, wherein the at least one additional energy layer involves an energy level that has not previously been used
adding (S14; S24) the at least one additional energy to the initial set, to produce an expanded candidate energy layer set
optimizing (S16; S26) a radiotherapy treatment plan based on the expanded candidate layer set.

公开(公告)号：US12133991B2

公开(公告)日：2024-11-05

申请号：US17907543

申请日：2021-03-22

Applicant: RAYSEARCH LABORATORIES AB

Inventor： Bjorn Andersson ,  Erik Engwall ,  Albin Fredriksson ,  Kjell Eriksson

IPC: A61N5/10

Abstract: A computer-based method of optimizing a radiotherapy treatment plan for a patient is proposed, wherein a treatment plan to be provided by one radiation set is optimized taking into account a previously delivered dose delivered by a different radiation set. One of the radiation sets is external beam radiotherapy and the other is brachytherapy.

公开(公告)号：US20220233883A1

公开(公告)日：2022-07-28

申请号：US17596506

申请日：2020-06-02

Applicant: RaySearch Laboratories AB

Inventor： Bjorn Andersson ,  Cecilia Battinelli ,  Rasmus Bokrantz

IPC: A61N5/10

Abstract: A method of radiotherapy treatment planning for particle-based arc treatment comprises the steps of determining (S11; S21) an initial set of candidate energy layers, performing a calculation on the initial set, determining (S13; S23), based on the outcome of said calculation, at least one additional energy layer to produce an expanded candidate layer set, wherein the at least one additional energy layer involves an energy level that has not previously been used adding (S14; S24) the at least one additional energy to the initial set, to produce an expanded candidate energy layer set optimizing (S16; S26) a radiotherapy treatment plan based on the expanded candidate layer set.