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公开(公告)号：US20140065598A1
公开(公告)日：2014-03-06
申请号：US13770521
申请日：2013-02-19
Applicant: RHEONIX, INC.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Greg Mouchka , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin
CPC classification number: C12Q1/6806 , B01L3/022 , B01L3/5027 , B01L3/502753 , B01L7/52 , B01L2200/0647 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2300/044 , B01L2300/0681 , B01L2300/0829 , B01L2300/0838 , B01L2300/0864 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2400/043 , B01L2400/0481 , B01L2400/0666 , C12Q1/6846 , C12Q1/686 , C12Q1/6883 , C12Q1/708 , G01N35/1002 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
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公开(公告)号：US20160222435A1
公开(公告)日：2016-08-04
申请号：US15061478
申请日：2016-03-04
Applicant: Rheonix, Inc.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin , Greg Mouchka
CPC classification number: C12Q1/686 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/10 , B01L2200/14 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/18 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6809 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/6846 , C12Q1/6876 , C12Q1/708 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N35/10 , G01N35/1002 , G01N2035/00346 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
Abstract translation: 独立的，完全自动化的生物测定执行装置包括壳体; 包括设置在所述壳体中的可控制的试剂分配系统的分配平台; 设置在所述壳体中的试剂供应部件; 气动歧管，其可移除地设置在所述壳体中的由所述分配平台共享的空间中，可拆卸地联接到流体输送层和多个储存器，其中所述流体输送层，所述储存器以及待引入其中的待测样品设置在 空间中的壳体与分配平台分离; 气动供给系统，其可拆卸地联接到与分配平台分离的空间中的壳体中的气动歧管; 以及耦合到所述分配平台和所述气动供应系统中的至少一个的控制系统，所述控制系统设置在所述壳体中。
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公开(公告)号：US20150307921A1
公开(公告)日：2015-10-29
申请号：US14798719
申请日：2015-07-14
Applicant: RHEONIX, INC.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin , Greg Mouchka
CPC classification number: C12Q1/686 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/10 , B01L2200/14 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/18 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6809 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/6846 , C12Q1/6876 , C12Q1/708 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N35/10 , G01N35/1002 , G01N2035/00346 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
Abstract translation: 独立的，完全自动化的生物测定执行装置包括壳体; 包括设置在所述壳体中的可控制的试剂分配系统的分配平台; 设置在所述壳体中的试剂供应部件; 气动歧管，其可移除地设置在所述壳体中的由所述分配平台共享的空间中，可拆卸地联接到流体输送层和多个储存器，其中所述流体输送层，所述储存器以及待引入其中的待测样品设置在 空间中的壳体与分配平台分离; 气动供给系统，其可拆卸地联接到与分配平台分离的空间中的壳体中的气动歧管; 以及耦合到所述分配平台和所述气动供应系统中的至少一个的控制系统，所述控制系统设置在所述壳体中。
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公开(公告)号：US09096890B2
公开(公告)日：2015-08-04
申请号：US13770521
申请日：2013-02-19
Applicant: RHEONIX, INC.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Greg Mouchka , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin
CPC classification number: C12Q1/6806 , B01L3/022 , B01L3/5027 , B01L3/502753 , B01L7/52 , B01L2200/0647 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2300/044 , B01L2300/0681 , B01L2300/0829 , B01L2300/0838 , B01L2300/0864 , B01L2300/0867 , B01L2300/0874 , B01L2300/088 , B01L2300/0887 , B01L2400/043 , B01L2400/0481 , B01L2400/0666 , C12Q1/6846 , C12Q1/686 , C12Q1/6883 , C12Q1/708 , G01N35/1002 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
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公开(公告)号：US08986614B2
公开(公告)日：2015-03-24
申请号：US13836032
申请日：2013-03-15
Applicant: Rheonix, Inc.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin , Greg Mouchka
CPC classification number: C12Q1/686 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/0668 , B01L2200/10 , B01L2200/14 , B01L2200/147 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/18 , B01L2300/1827 , B01L2400/043 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6809 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/6846 , C12Q1/6876 , C12Q1/708 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N35/10 , G01N35/1002 , G01N2035/00346 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
Abstract translation: 独立的，完全自动化的生物测定执行装置包括壳体; 包括设置在所述壳体中的可控制的试剂分配系统的分配平台; 设置在所述壳体中的试剂供应部件; 气动歧管，其可移除地设置在所述壳体中的由所述分配平台共享的空间中，可拆卸地联接到流体输送层和多个储存器，其中所述流体输送层，所述储存器以及待引入其中的待测样品设置在 空间中的壳体与分配平台分离; 气动供给系统，其可拆卸地联接到与分配平台分离的空间中的壳体中的气动歧管; 以及耦合到所述分配平台和所述气动供应系统中的至少一个的控制系统，所述控制系统设置在所述壳体中。
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Patent Agency Ranking
公开(公告)号：US09328381B2
公开(公告)日：2016-05-03
申请号：US14798719
申请日：2015-07-14
Applicant: RHEONIX, INC.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin , Greg Mouchka
CPC classification number: C12Q1/686 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/10 , B01L2200/14 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/18 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6809 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/6846 , C12Q1/6876 , C12Q1/708 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N35/10 , G01N35/1002 , G01N2035/00346 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
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公开(公告)号：US20140206009A1
公开(公告)日：2014-07-24
申请号：US14226204
申请日：2014-03-26
Applicant: RHEONIX, INC.
Inventor： Lincoln C. Young , Peng Zhou , Gwendolyn Spizz , Rubina Yasmin
CPC classification number: C12N15/1013 , C12Q1/6806
Abstract: A method is provided for purifying nucleic acid from a sample in a microfluidic device. The method can be used to purify nucleic acids from any source known in the art that comprises nucleic acids, such as prokaryotic or eukaryotic organisms, viruses, cell, tissues, organs, etc. In a specific example, the tissue is whole blood. The method for purifying nucleic acid may run fully automated in the microfluidic device.
Abstract translation: 提供了一种用于从微流体装置中的样品中纯化核酸的方法。 该方法可用于从本领域已知的任何来源纯化核酸，其包含核酸，例如原核或真核生物，病毒，细胞，组织，器官等。在具体实例中，组织是全血。 纯化核酸的方法可以在微流体装置中完全自动化。
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公开(公告)号：US09556478B2
公开(公告)日：2017-01-31
申请号：US15061478
申请日：2016-03-04
Applicant: Rheonix, Inc.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin , Greg Mouchka
CPC classification number: C12Q1/686 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/10 , B01L2200/14 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/18 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6809 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/6846 , C12Q1/6876 , C12Q1/708 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N35/10 , G01N35/1002 , G01N2035/00346 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
Abstract translation: 独立的，完全自动化的生物测定执行装置包括壳体; 包括设置在所述壳体中的可控制的试剂分配系统的分配平台; 设置在所述壳体中的试剂供应部件; 气动歧管，其可移除地设置在所述壳体中的由所述分配平台共享的空间中，可拆卸地联接到流体输送层和多个储存器，其中所述流体输送层，所述储存器以及待引入其中的待测样品设置在 空间中的壳体与分配平台分离; 气动供给系统，其可拆卸地联接到与分配平台分离的空间中的壳体中的气动歧管; 以及耦合到所述分配平台和所述气动供应系统中的至少一个的控制系统，所述控制系统设置在所述壳体中。
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公开(公告)号：US09169479B2
公开(公告)日：2015-10-27
申请号：US14226204
申请日：2014-03-26
Applicant: RHEONIX, INC.
Inventor： Lincoln C. Young , Peng Zhou , Gwendolyn Spizz , Rubina Yasmin
CPC classification number: C12N15/1013 , C12Q1/6806
Abstract: A method is provided for purifying nucleic acid from a sample in a microfluidic device. The method can be used to purify nucleic acids from any source known in the art that comprises nucleic acids, such as prokaryotic or eukaryotic organisms, viruses, cell, tissues, organs, etc. In a specific example, the tissue is whole blood. The method for purifying nucleic acid may run fully automated in the microfluidic device.
Abstract translation: 提供了一种用于从微流体装置中的样品中纯化核酸的方法。 该方法可用于从本领域已知的任何来源纯化核酸，其包含核酸，例如原核或真核生物，病毒，细胞，组织，器官等。在具体实例中，组织是全血。 纯化核酸的方法可以在微流体装置中完全自动化。
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公开(公告)号：US09102979B2
公开(公告)日：2015-08-11
申请号：US14609697
申请日：2015-01-30
Applicant: RHEONIX, INC.
Inventor： Peng Zhou , Lincoln C. Young , Benjamin Thomas , Zongyuan Chen , Todd Roswech , Gwendolyn Spizz , Rubina Yasmin , Greg Mouchka
CPC classification number: C12Q1/686 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/10 , B01L2200/14 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0819 , B01L2300/0861 , B01L2300/18 , B01L2400/0481 , B01L2400/0487 , B01L2400/0655 , C12Q1/6809 , C12Q1/6813 , C12Q1/6825 , C12Q1/6837 , C12Q1/6846 , C12Q1/6876 , C12Q1/708 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N35/10 , G01N35/1002 , G01N2035/00346 , C12Q2565/629
Abstract: A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.
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