公开(公告)号：US20010000143A1

公开(公告)日：2001-04-05

申请号：US09726876

申请日：2000-11-30

Applicant: ROCHE VITAMINS INC.

Inventor： Alexander Bausch ,  Siegfried K. F. Peter ,  Kurt Steiner ,  Hansjorg Stoller ,  Eckhard Weidner

IPC: B01J002/00 ,  B01J002/04 ,  B01J002/06 ,  B29B009/00 ,  A61K009/14

CPC classification number: C07C403/24 ,  A61K9/146 ,  A61K9/1641 ,  A61K9/1688 ,  A61K31/015 ,  B01F2003/125 ,  Y02P20/544

Abstract: A process for producing pulverous, i.e., powdered, preparations from sparingly soluble solid materials is disclosed. The process utilizes dimethyl ether under conditions of elevated temperature and pressure to dissolve the solid material. Upon release of the pressure, the solid material precipitates as a fine powder and the gaseous dimethyl ether is released or drawn off.

公开(公告)号：US20020086059A1

公开(公告)日：2002-07-04

申请号：US10045270

申请日：2001-10-23

Applicant: ROCHE VITAMINS INC.

Inventor： Alexander Bausch ,  Siegfried K.F. Peter ,  Kurt Steiner ,  Hansjorg Stoller ,  Eckhard Weidner

IPC: A61K009/14

CPC classification number: C07C403/24 ,  A61K9/146 ,  A61K9/1641 ,  A61K9/1688 ,  A61K31/015 ,  B01F2003/125 ,  Y02P20/544

Abstract: A process for producing pulverous, i.e., powdered, preparations from sparingly soluble solid materials is disclosed. The process utilizes dimethyl ether under conditions of elevated temperature and pressure to dissolve the solid material. Upon release of the pressure, the solid material precipitates as a fine powder and the gaseous dimethyl ether is released or drawn off.

Abstract translation: 公开了从微溶固体材料制备粉状，即粉末状制剂的方法。 该方法在升高的温度和压力的条件下使用二甲醚以溶解固体材料。 释放压力后，固体物质作为细粉末析出，气态二甲醚被释放或排出。