公开(公告)号：US20160287147A1

公开(公告)日：2016-10-06

申请号：US15182455

申请日：2016-06-14

Applicant: RSP SYSTEMS A/S

Inventor： Morten HENNEBERG ,  Stefan Ovesen BANKE ,  Anders WEBER

IPC: A61B5/1455 ,  A61B5/145

CPC classification number: A61B5/1455 ,  A61B5/0059 ,  A61B5/0068 ,  A61B5/0075 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/441 ,  A61B2562/0238 ,  A61B2562/0242 ,  A61B2562/146 ,  G01N21/65

Abstract: A metabolite concentration is measured in vivo using Raman spectroscopy in such a way as to receive at a detector light scattered from the metabolite in interstitial fluid in skin in a measurement location at a depth of from 200-300 μm below the skin surface providing improved retention of correct calibration and transferability of calibration between individual subjects.

Abstract translation: 使用拉曼光谱法在体内测量代谢物浓度，使得在距离皮肤表面200-300μm深度的测量位置处接收来自皮肤间隙液中的代谢物散射的检测器光，从而提供改善的保留 正确的校准和个体对象之间校准的可转移性。