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    DETERMINING A DISTRIBUTION OF SPOTS OF VARYING SIZES FOR ION BEAM THERAPY BASED ON USER CONFIGURATION
    2.
    发明申请
    DETERMINING A DISTRIBUTION OF SPOTS OF VARYING SIZES FOR ION BEAM THERAPY BASED ON USER CONFIGURATION 审中-公开

    公开(公告)号：US20200147410A1

    公开(公告)日：2020-05-14

    申请号：US16625895

    申请日：2018-06-26

    Applicant: RaySearch Laboratories AB

    Inventor： Erik ENGWALL ,  Lars GLIMELIUS ,  Martin JANSON

    IPC: A61N5/10

    Abstract: It is provided a method for determining a distribution of spots for use with ion beam therapy for providing the spots in a target volume, wherein each spot represents a collection of ions of a specific energy level and of a specific size at a specific lateral location. The method is performed in a treatment planning system and comprises the steps of: dividing the target volume in a plurality of target sections based on a user configuration comprising at least one spot size strategy defining a maximum spot size at the location of a Bragg peak; assigning a spot size strategy to each one of the target sections based on the location of the respective target section; and determining, within each target section, spots in accordance with its spot size strategy.

    OBTAINING AN ENERGY SPECTRUM OF A FOCUSED ION BEAM
    3.
    发明申请
    OBTAINING AN ENERGY SPECTRUM OF A FOCUSED ION BEAM 有权

    公开(公告)号：US20210159047A1

    公开(公告)日：2021-05-27

    申请号：US17097199

    申请日：2020-11-13

    Applicant: RaySearch Laboratories AB

    Inventor： Martin JANSON

    IPC: H01J37/304 ,  H01J37/05

    Abstract: It is provided a method for obtaining an energy spectrum of a focused ion beam when a Bragg peak chamber is used to measure an integrated depth dose, IDD. The method comprises the steps of: simulating doses of a set of nominally mono energetic focused ion beams; determining a lateral extension of a Bragg peak chamber to evaluate; calculating a set of theoretic component IDD curves, CIDDs, by laterally integrating the dose of the simulated set of the nominally mono energetic focused ion beams, over the lateral extension of the Bragg peak chamber; storing calculated CIDDs; obtaining a measured IDD of a focused ion beam with a nominal energy using the Bragg peak chamber; and performing a fit of a linear combination of CIDDs to the measured IDD, to determine an energy spectrum for the focused ion beam with the nominal beam energy.

    Robust treatment planning or plan evaluation
    4.
    发明公开
    Robust treatment planning or plan evaluation 审中-公开

    公开(公告)号：US20230285775A1

    公开(公告)日：2023-09-14

    申请号：US18005674

    申请日：2021-06-14

    Applicant: RaySearch Laboratories AB (Publ)

    Inventor： Martin JANSON ,  Agnes ANGERUD

    IPC: A61N5/10 ,  G16H20/40

    CPC classification number: A61N5/1038 ,  G16H20/40

    Abstract: In cases where material properties of a structure within or outside a patient receiving radiotherapy treatment, robust planning can be used, based on different scenarios with different material property values using a material override function present in the treatment planning system.
    A computer-based method of generating a radiotherapy treatment plan for a patient, based on an image of the patient and a desired dose. In cases where material properties of a structure within or outside a patient receiving radiotherapy treatment, robust planning can be used, based on different scenarios with different material property values using a material override function present in the treatment planning system. Robust planning is performed based on the at least two scenarios to provide robust evaluation data for each of the at least two scenarios and/or a robust optimized treatment plan with respect to all values in the set of material override values.

    TREATMENT PLANNING USING MULTIPLE RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) MODELS
    5.
    发明公开
    TREATMENT PLANNING USING MULTIPLE RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) MODELS 审中-公开

    公开(公告)号：US20230211177A1

    公开(公告)日：2023-07-06

    申请号：US17996620

    申请日：2021-04-09

    Applicant: RaySearch Laboratories AB (Publ)

    Inventor： Martin JANSON ,  Albin FREDRIKSSON ,  Erik TRANEUS ,  Kjell ERIKSSON

    IPC: A61N5/10 ,  G16H20/40

    CPC classification number: A61N5/1031 ,  G16H20/40 ,  A61N2005/1087

    Abstract: An inverse-planning method (100), by which a treatment plan specifying a non-photon irradiation of a patient including a target volume is generated, comprises: obtaining (110, 112) first and second plan goals in terms of a respective first and second numerical condition on the treatment plan’s photon-equivalent dose as computed using a first and second RBE factor; and generating (114) the treatment plan by an optimization process aiming to satisfy the first, second and any further plan goals, wherein (a) the first and second plan goals apply to volumes which either are included in the TV or are completely or partially separate from the TV and/or (b) the first and second RBE factors are variable. In a further aspect, a data carrier provides a treatment plan with these characteristics together with reporting quantities relating to fulfilment of the first and second plan goals.

    ASSIGNING RIPPLE FILTER SETTINGS
    6.
    发明申请
    ASSIGNING RIPPLE FILTER SETTINGS 有权

    公开(公告)号：US20210154492A1

    公开(公告)日：2021-05-27

    申请号：US16625988

    申请日：2018-06-28

    Applicant: RaySearch Laboratories AB

    Inventor： Erik ENGWALL ,  Martin JANSON ,  Lars GLIMELIUS

    IPC: A61N5/10

    Abstract: It is provided a method for determining ripple filter settings for an ion therapy beam being capable of providing ions of different energy levels to a target volume. The method is performed in a treatment planning system and comprises the steps of: determining at least one beam direction to use to cover a target volume; and assigning a ripple filter setting to each one of a plurality of sub-beams of each one of the at least one beam direction such that each sub-beam is assigned a different ripple filter setting, wherein each ripple filter setting results in a different effect on a Bragg peak width in a direction along the beam, and each energy level is assigned to one of the plurality of sub-beams. The step of assigning a ripple filter setting comprises optimizing based on different filter settings for different sub-beams for each beam direction.

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