公开(公告)号：US09207178B2

公开(公告)日：2015-12-08

申请号：US13630046

申请日：2012-09-28

Applicant: SMOBIO Technology, Inc.

Inventor： Kuan-Lin Lee ,  Chen-Sheng Wu ,  Chun-Hsien Kuo

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01N2021/6417 ,  G01N2021/6471 ,  G01N2201/0627 ,  G01N2201/0634

Abstract: A double-light cabinet for testing a biological sample labeled with fluorochrome includes a case, in which a light unit and a diffusion unit are received. The light unit has two spot light sources to emit spot lights with specified wavelengths according to the test, and the diffusion unit diffuses the spot lights into surface lights, to which that the biological sample is exposed. The present invention further includes an amber filter unit to filter the surface light to enhance the signal of biological samples. Using the lights with specified wavelengths, the present invention may serve both functions of excitation and illumination of the biological sample.

Abstract translation: 用于测试用荧光染料标记的生物样品的双灯柜包括其中接收光单元和扩散单元的壳体。 光单元具有两个点光源，以根据测试发射具有特定波长的点光源，并且扩散单元将聚光灯扩散到生物样品暴露于的表面光。 本发明还包括琥珀色滤光器单元，用于过滤表面光以增强生物样品的信号。 使用具有特定波长的光，本发明可以起到生物样品的激发和照射的功能。

公开(公告)号：US20230075082A1

公开(公告)日：2023-03-09

申请号：US17690386

申请日：2022-03-09

Applicant: SMOBIO Technology, Inc.

Inventor： Kuan-Lin Lee

IPC: C12P19/34 ,  C12N15/10 ,  C12N9/00

Abstract: The present invention provides a method for synthesizing DNA, which includes: (a) providing an oligonucleotide components library as a material for synthesizing DNA, wherein an oligonucleotide component is a short oligonucleotide chain whose new end and trailing end are OH groups; (b) analyzing sequence information of a DNA to be synthesized to obtain an oligonucleotide components combination order; (c) using the oligonucleotide components library to arrange an oligonucleotide component order according to the oligonucleotide components combination order; (d) phosphorylating the new end of a first-order oligonucleotide; (e) combining the first-order oligonucleotide with a complementary oligonucleotide of the first-order oligonucleotide to obtain a first-order double-stranded oligonucleotide; (f) combining a second-order oligonucleotide in the oligonucleotide components combination order with a complementary oligonucleotide of the second-order oligonucleotide to obtain a second-order double-stranded oligonucleotide; (g) ligating the phosphorylated new end of the first-order oligonucleotide with the trailing end of the second-order oligonucleotide to obtain a synthetic oligonucleotide having an OH group as the new end; and (h) repeating the above steps (d) to (g) to sequentially elongate the synthetic oligonucleotide until the DNA sequence to be synthesized is completed.

公开(公告)号：US09568426B2

公开(公告)日：2017-02-14

申请号：US14271226

申请日：2014-05-06

Applicant: SMOBIO TECHNOLOGY, INC.

Inventor： Chen-Sheng Wu ,  Chun-Hsien Kuo ,  Kuan-Lin Lee

IPC: F21V15/00 ,  G01N21/64 ,  F21V8/00

CPC classification number: G01N21/6447 ,  G01N21/645 ,  G01N2201/02 ,  G01N2201/062 ,  G01N2201/08 ,  G02B6/003

Abstract: A cabinet capable of guiding light, which is used for detecting a biological sample strained with a fluorescent dye, includes a main body, at least one light source, and at least one light guiding structure. The main body has a sample table to place the biological sample. The at least one light source is provided on the main body and near the sample table, wherein the at least one light source provides light required to excite the fluorescent dye incorporated in the biological sample. The at least one light guiding structure is provided between the sample table and the at least one light source to refract the light provided by the at least one light source onto the sample table and the biological sample. Whereby, the biological sample is exposed to more light, and therefore the intensity of the light released from the biological sample is enhanced.

Abstract translation: 用于检测应变荧光染料的生物样品的能够引导光的机壳包括主体，至少一个光源和至少一个导光结构。 主体有一个放置生物样品的样品台。 所述至少一个光源设置在所述主体上并且靠近所述样品台，其中所述至少一个光源提供激发掺入所述生物样品中的荧光染料所需的光。 所述至少一个导光结构设置在所述样品台和所述至少一个光源之间，以将由所述至少一个光源提供的光折射到所述样品台和所述生物样品上。 因此，生物样品暴露于更多的光，因此从生物样品释放的光的强度增强。