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公开(公告)号:US12152979B2
公开(公告)日:2024-11-26
申请号:US17520107
申请日:2021-11-05
Applicant: SOL INC.
Inventor: Jong Muk Lee
IPC: G01N15/10 , G01N15/14 , G01N15/1433 , G01N15/1434 , G06T11/20 , G01N15/01
Abstract: An image sensor package, a system, and a method for counting fine particles by using a virtual grid line are provided. The image sensor package includes an image sensor array, a grid pattern layer formed on an outer area of the image sensor array and including a plurality of protruding patterns spaced apart from each other while protruding toward the central area of the image sensor array to form a virtual grid line, a dam pattern layer formed on the grid pattern layer, having a specific height, and configured to form a channel or a chamber for receiving the fine particles to be counted, and a cover glass formed on the dam pattern layer.
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公开(公告)号:US12159473B2
公开(公告)日:2024-12-03
申请号:US18176893
申请日:2023-03-01
Applicant: SOL INC.
Inventor: Jong Muk Lee , Hee Chan Shin , Seong Won Kwon , Ki Ho Jang
IPC: G06V10/143 , G01N21/31 , G02B21/00 , G06V20/69 , G01N21/17
Abstract: Provided are a device for analyzing a large-area sample based on an image, a device for analyzing a sample based on an image by using a difference in medium characteristic, and a method for measuring and analyzing a sample by using the same. The device for analyzing a large-area sample includes a first sensor array including sensors disposed while being spaced apart from each other in a first direction, a second sensor array including sensors disposed while being spaced apart from each other in the first direction, and spaced apart from the first sensor array in a second direction, and a control unit that obtains image data for a cell included in the sample by using sensing data of the sensor on the sample, in which the sample is interposed between the first sensor array and the second sensor array.
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公开(公告)号:US11879845B2
公开(公告)日:2024-01-23
申请号:US17556370
申请日:2021-12-20
Applicant: SOL INC.
Inventor: Jong Muk Lee
CPC classification number: G01N21/6486 , G01N21/1717 , G01N21/91 , G01N2021/174 , G01N2021/6471
Abstract: The present disclosure relates to a fluorescence filter for measuring fluorescence generated by a measurement object and an image sensor module including the same, and includes an absorption filter transmitting light within a specific wavelength band generated by the measurement object including a fluorescent dye and absorbs light in the remaining wavelength bands, and a reflection filter that is disposed adjacent to the absorption filter, transmits light within a specific wavelength band generated by the measurement object, and reflects light in the remaining wavelength bands, wherein the absorption filter has a plurality of wells having a predetermined depth in which the measurement object is accommodated, and wherein the plurality of wells are disposed at regular intervals on an incident surface of the absorption filter to which external light is incident.
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公开(公告)号:US12158410B2
公开(公告)日:2024-12-03
申请号:US17106961
申请日:2020-11-30
Applicant: SOL INC. , Government of the United States of America, as Represented by the Secretary of Commerce
Inventor: Jong Muk Lee , Darwin R. Reyes-Hernandez , Brian J. Nablo
IPC: G01N15/1433 , G01N15/14 , G01N15/1434 , G01N33/50
Abstract: The present disclosure relates to a real-time quantification method of cell viability through a supravital dye uptake using a lens-free imaging system. The method includes a step of incubating a sample cell in a cell culture medium, steps of detecting light penetrating the cell culture medium and identifying a boundary region of the sample cell at a preset time interval based on the detected light, a step of staining the incubated sample cell with the supravital dye, a step of detecting intensity of light penetrating the cell culture medium at a preset time interval, a step of calculating absorbance of the sample cell included in the cell culture medium at a preset time interval based on the boundary region and the detected intensity of light and a step of analyzing a viability of the sample cell based on the calculated absorbance.
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公开(公告)号:US11112301B2
公开(公告)日:2021-09-07
申请号:US15577586
申请日:2016-06-09
Applicant: SOL INC.
Inventor: Jong Muk Lee , Tae Young Lee , Jae In Kim
Abstract: The present invention relates to a method for correcting a packaged optical sensor array module, and the method for correcting a packaged optical sensor array module according to the present invention comprises the steps of: analyzing statistical characteristics of an optical sensor array with respect to light emitted from a standard light source having a predetermined characteristic value to extract a representative value, and calculating a first correction value for a measurement value according to the extracted representative value; and calculating a second correction value for a measured value of the optical sensor array that is corrected by the first correction value with respect to light emitted from an applied light source or light emitted by a fluorescence of the applied light source.
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公开(公告)号:US11680850B2
公开(公告)日:2023-06-20
申请号:US17388863
申请日:2021-07-29
Applicant: SOL INC.
Inventor: Jong Muk Lee , Tae Young Lee , Jae In Kim
IPC: G01J1/44 , H04N5/365 , H01L27/146 , G01N21/64 , H04N5/357 , H04N5/374 , H04N25/60 , H04N25/76 , H04N25/671 , H04N25/672 , H04N25/673
CPC classification number: G01J1/44 , G01N21/6428 , G01N21/6458 , H01L27/146 , H04N25/60 , H04N25/671 , H04N25/672 , H04N25/673 , H04N25/76 , G01J2001/444 , G01N2201/062
Abstract: The present invention relates to a method for correcting a packaged optical sensor array module, and the method for correcting a packaged optical sensor array module according to the present invention comprises the steps of: analyzing statistical characteristics of an optical sensor array with respect to light emitted from a standard light source having a predetermined characteristic value to extract a representative value, and calculating a first correction value for a measurement value according to the extracted representative value; and calculating a second correction value for a measured value of the optical sensor array that is corrected by the first correction value with respect to light emitted from an applied light source or light emitted by a fluorescence of the applied light source.
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公开(公告)号:US11624899B2
公开(公告)日:2023-04-11
申请号:US17106084
申请日:2020-11-28
Applicant: SOL INC.
Inventor: Jong Muk Lee , Hee Chan Shin , Seong Won Kwon , Ki Ho Jang
Abstract: Provided are a device for analyzing a large-area sample based on an image, a device for analyzing a sample based on an image by using a difference in medium characteristic, and a method for measuring and analyzing a sample by using the same. The device for analyzing a large-area sample includes a first sensor array including a plurality of sensors which are disposed while being spaced apart from each other in a first direction, a second sensor array including a plurality of sensors, which are disposed while being spaced apart from each other in the first direction, and spaced apart from the first sensor array in a second direction, and a control unit to obtain image data for a cell included in the sample by using sensing data of the sensor on the sample, in which the sample is interposed between the first sensor array and the second sensor array. An active area of one of the sensor in the first sensor array overlaps an active area of one of the sensors in the second sensor array, in the second direction.
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公开(公告)号:US11137335B2
公开(公告)日:2021-10-05
申请号:US16338064
申请日:2017-09-29
Applicant: SOL INC.
Inventor: Jong Muk Lee , Seong Won Kwon , Ki Ho Jang , Jung Joon Ahn , Tae Young Lee
Abstract: Provided is a method for evaluating fluid flow characteristics of a lens-free complementary metal-oxide semiconductor (CMOS) optical sensor package module with a flow channel. The method includes: measuring a propagation profile and a flow velocity in an initial state flow of a fluid in the flow channel; calculating a first statistical parameter relating to flow characteristics of the fluid from the measured propagation profile and flow velocity; and comparing the calculated first statistical parameter with a preset reference value and evaluating quality of the flow channel according to the comparison result.
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