公开(公告)号：US20190330685A1

公开(公告)日：2019-10-31

申请号：US16310074

申请日：2017-06-15

Applicant: STRECK, INC.

Inventor： Maria Torres ,  Nancy Hanson ,  Joel Lechner ,  Stephanie Cossette ,  Cathy Scheer ,  Matthew R. Kreifels ,  Stacey Morrow ,  Christopher Connelly ,  Laura R. Porter ,  Randy Fowler

IPC: C12Q1/689 ,  C12Q1/686 ,  C12Q1/6809 ,  C12Q1/6837 ,  C12Q1/6851

Abstract: Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple β-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of β-lactamase genes selected from the group consisting of one or more of the following: MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51-like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.