公开(公告)号：US20170003310A1

公开(公告)日：2017-01-05

申请号：US15190714

申请日：2016-06-23

Applicant: Sysmex Corporation

Inventor： Keiichiro Shohmi ,  Ryousuke ISHITSUBO ,  Shoichiro ASADA

IPC: G01N35/10

CPC classification number: G01N35/1011 ,  B01L3/0237 ,  B01L3/0279 ,  B01L3/5085 ,  B01L7/52 ,  B01L9/523 ,  B01L2200/16 ,  B01L2300/021 ,  B01L2300/0829 ,  B01L2400/043 ,  G01N35/0098 ,  G01N35/1002 ,  G01N35/1065 ,  G01N35/1081 ,  G01N2035/00564 ,  G01N2035/00574

Abstract: Disclosed is a specimen processing apparatus for genetic testing. The apparatus includes: a mode setting section configured to receive a setting of an operation mode from: an emulsion preparation mode for preparing a water-in-oil type (W/O type) emulsion having dispersed therein a plurality of droplets, each droplet containing a specimen which contains DNA and a bead to which a reagent component necessary for amplifying a target DNA molecule is bound; and an emulsion breaking mode for breaking the emulsion and collecting beads from the droplets; and a controller programmed to control the transfer unit and the dispensing unit in accordance with the operation mode set by the mode setting section.

Abstract translation: 公开了一种用于遗传检测的标本处理装置。 该装置包括：模式设定部，被配置为从以下步骤接收操作模式的设定：用于制备分散有多个液滴的油包水型（W / O型）乳液的乳液制备模式，每个液滴包含 包含用于扩增靶DNA分子所必需的试剂成分的DNA和珠的标本; 以及用于破碎乳液并从液滴收集珠粒的乳液破碎模式; 以及控制器，被编程为根据由模式设置部分设置的操作模式来控制传送单元和分配单元。

公开(公告)号：US20180149667A1

公开(公告)日：2018-05-31

申请号：US15823652

申请日：2017-11-28

Applicant: SYSMEX CORPORATION

Inventor： Yuto SASAKI ,  Kazuki ASAO ,  Kazuyuki IGUCHI ,  Keiichiro SHOHMI ,  Shoichiro ASADA ,  Hiroaki TOBIMATSU ,  Ryutaro SHINYA

IPC: G01N35/02 ,  B01L9/00 ,  G01N35/04

CPC classification number: G01N35/026 ,  B01L9/00 ,  B01L9/523 ,  B01L2200/025 ,  B01L2300/0829 ,  G01N35/04 ,  G01N2035/0415 ,  G01N2035/042 ,  G01N2035/0465

Abstract: A specimen transport apparatus according to an embodiment includes: a holder including first and second trenches and configured to hold a specimen; a first transporter including a first protrusion to engage with the first trench and configured to transport the holder by transferring the first protrusion engaged with the first trench in an extension direction of the second trench; a second transporter including a second protrusion to engage with the second trench and configured to transport the holder by transferring the second protrusion engaged with the second trench in an extension direction of the first trench. The first trench is formed in at least one of an upper surface and a lower surface of the holder. The second trench is formed in at least one of the upper surface and the lower surface of the holder, and is formed to extend to a lateral surface of the holder.

公开(公告)号：US20140295453A1

公开(公告)日：2014-10-02

申请号：US14226249

申请日：2014-03-26

Applicant: SYSMEX CORPORATION

Inventor： Tsukasa HIRATA ,  Shoichiro ASADA ,  Naoya MAEDA ,  Kosuke YAMAGUCHI

IPC: G01N33/53

CPC classification number: G01N33/5302 ,  G01N35/00584 ,  G01N35/00693 ,  G01N2035/00673 ,  G01N2035/00891

Abstract: To provide a sample analyzer capable of accurately obtaining the number of analyzable samples. When analyzing a sample collected from a subject, a CPU of the sample analyzer calculates the number of analyzable samples based on a remaining number of tests of a reagent set in a reagent holding section and the number of tests of the reagent to be consumed in measurement of a control, and causes a output section to display the number of analyzable samples. When creating a calibration curve, the CPU calculates the number of analyzable samples based on a remaining number of tests of the reagent set in the reagent holding section, the number of tests of the reagent to be consumed in measurement of the control, and the number of tests of the reagent to be consumed in measurement of a calibrator, and causes the output section to display the number of analyzable samples.

Abstract translation: 提供能够准确地获得可分析样品数量的样品分析仪。 当对从被检体收集的样本进行分析时，样本分析装置的CPU基于在试剂保存部中设定的试剂的剩余次数和测定中要消耗的试剂的次数来计算可分析样品的个数 并且使得输出部分显示可分析样本的数量。 当创建校准曲线时，CPU根据试剂保留部分中设定的试剂的剩余试验次数，测量控制中要消耗的试剂的次数和数量计算可分析样品的数量 在校准器的测量中要消耗的试剂的测试，并且使得输出部分显示可分析样品的数量。

公开(公告)号：US20230314300A1

公开(公告)日：2023-10-05

申请号：US18185589

申请日：2023-03-17

Applicant: Sysmex Corporation

Inventor： Shoichiro ASADA ,  Konobu Kimura ,  Masamichi Tanaka ,  Kenichiro Suzuki ,  Kohel Nango

IPC: G01N15/14

CPC classification number: G01N15/1434 ,  G01N2015/0065

Abstract: Provided is a cell analysis method and a cell analyzer that, in a configuration in which data obtained from a plurality of cells contained in a specimen is analyzed, can process, at a requested throughput, data of cells having a significantly increased information amount. The cell analysis method, using a cell analyzer that comprises a host processor and a parallel-processing processor, includes: obtaining, on the basis of control by the host processor, data regarding each of a plurality of cells in a specimen; executing, by the parallel-processing processor, parallel processing regarding the data; and generating, on the basis of a result of the parallel processing, information regarding a cell type with respect to each of the plurality of cells.

公开(公告)号：US20140056783A1

公开(公告)日：2014-02-27

申请号：US13971451

申请日：2013-08-20

Applicant: SYSMEX CORPORATION

Inventor： Katsuhiko JINDO ,  Yoshinori OOI ,  Shoichiro ASADA ,  Daijyu OBINATA

IPC: G01N1/28

CPC classification number: G01N1/28 ,  C12M45/02 ,  G01N1/286

Abstract: Disclosed is a homogenizer comprising: a crushing part having a blender for crushing a tissue sample in a container; a rotation driver configured to rotate the blender in contact with the tissue sample; and an absorbing part for absorbing a pressure applied to the tissue sample, which is caused when the blender comes into contact with the tissue sample.

Abstract translation: 公开了一种均质器，其包括：破碎部，其具有用于在容器中破碎组织样品的混合器; 旋转驱动器，其构造成使所述搅拌器旋转与所述组织样品接触; 以及用于吸收施加到组织样品上的压力的吸收部件，其在所述搅拌器与所述组织样品接触时引起。

公开(公告)号：US20230221238A1

公开(公告)日：2023-07-13

申请号：US18185814

申请日：2023-03-17

Applicant: SYSMEX CORPORATION

Inventor： Shoichiro ASADA ,  Konobu KIMURA ,  Masamichi TANAKA ,  Kenichiro SUZUKI ,  Kohei NANGO

IPC: G01N15/14

CPC classification number: G01N15/1459 ,  G01N15/1475

Abstract: In a configuration for analyzing data of cells measured by a cell measuring apparatus, accuracy of cell classification is improved without requiring the cell measuring apparatus to have high information processing capability. A cell analysis method, using a cell analyzer for analyzing cells in accordance with an artificial intelligence algorithm, includes: obtaining the data regarding the cells measured by the cell measuring apparatus; analyzing the data to generate information regarding a cell type of each of the cells; and transmitting the information to the cell measuring apparatus.

公开(公告)号：US20220003745A1

公开(公告)日：2022-01-06

申请号：US17480683

申请日：2021-09-21

Applicant: SYSMEX CORPORATION

Inventor： Konobu KIMURA ,  Masamichi TANAKA ,  Shoichiro ASADA

IPC: G01N33/487 ,  G06N3/02 ,  G01N15/14

Abstract: The types of cells that cannot be determined by use of a conventional scattergram are determined. The problem is solved by a cell analysis method for analyzing cells contained in a biological sample, by using a deep learning algorithm having a neural network structure, the cell analysis method including: causing the cells to flow in a flow path; obtaining a signal strength of a signal regarding each of the individual cells passing through the flow path, and inputting, into the deep learning algorithm, numerical data corresponding to the obtained signal strength regarding each of the individual cells; and on the basis of a result outputted from the deep learning algorithm, determining, for each cell, a type of the cell for which the signal strength has been obtained.

公开(公告)号：US20150114140A1

公开(公告)日：2015-04-30

申请号：US14527100

申请日：2014-10-29

Applicant: Sysmex Corporation

Inventor： Takeo OKUYAMA ,  Shoichiro ASADA ,  Tsukasa HIRATA ,  Kazuki ASAO

IPC: G01N35/10 ,  G01N1/00

CPC classification number: G01N35/1011 ,  G01N35/1016 ,  G01N2035/1025

Abstract: Disclosed is a method for adjusting a position of an aspirator in a sample processing apparatus, the sample processing apparatus comprising the aspirator configured to aspirate a sample or a reagent from a container and a capacitance sensor connected to the aspirator to detect change in capacitance, the method comprising: moving the aspirator above a position adjustment part which is electrically conductive and which is disposed at a predetermined position; obtaining capacitance detected by the capacitance sensor while moving the aspirator; and setting reference position information indicating a reference position of the aspirator based on change in the obtained capacitance.

Abstract translation: 公开了一种用于调节样品处理装置中抽吸器的位置的方法，所述样品处理设备包括被配置为从容器抽吸样品或试剂的抽吸器和连接到抽吸器的电容传感器以检测电容的变化， 方法包括：将吸气器移动到导电的位置调节部分上方，并将其设置在预定位置; 在移动吸气器的同时获得由电容传感器检测的电容; 并且基于所获得的电容的变化来设置指示吸气器的参考位置的参考位置信息。

公开(公告)号：US20130258800A1

公开(公告)日：2013-10-03

申请号：US13851549

申请日：2013-03-27

Applicant: SYSMEX CORPORATION

Inventor： Katsuhiko JINDO ,  Yoshinori OOI ,  Shoichiro ASADA ,  Daijyu OBINATA ,  Keiichiro SHOHMI

IPC: C12M1/33

CPC classification number: C12M45/02 ,  B01F13/1022 ,  B01F13/1041 ,  B01F15/065 ,  C12M47/08 ,  C12M47/20

Abstract: A homogenizer, for homogenizing a tissue sample collected from a living body, comprising: a main body; and a storage cooler, comprising a container holder for holding a sample container, configured to cool a tissue sample in the sample container held by the container holder, the storage cooler being detachably installed to the main body, wherein the main body has a blender for crushing the tissue sample in the sample container held in the storage cooler is disclosed.

Abstract translation: 一种均质器，用于使从活体收集的组织样本均质化，包括：主体; 以及存储冷却器，其特征在于，具备容纳容器保持件，所述容器保持件用于容纳样本容器，所述容器保持器构造为冷却由所述容器保持件保持的样本容器中的组织样本，所述储存冷却器可拆卸地安装在所述主体上，其中，所述主体具有： 公开了在保持在储存冷却器中的样品容器中破碎组织样品。