MICROFLUIDIC DEVICE FOR SINGLE CELL PROCESSING AND METHOD AND SYSTEM FOR SINGLE CELL BIOPHYSICAL PHENOTYPING USING THE MICROFLUIDIC DEVICE

    公开(公告)号:US20220187184A1

    公开(公告)日:2022-06-16

    申请号:US17436101

    申请日:2020-03-05

    Inventor: Ye AL Dahou YANG

    Abstract: A microfluidic device includes a substrate; a plurality of electrode channels, including a first electrode channel, a second electrode channel, a third electrode channel and a fourth electrode channel, each containing an electrode material to form an electrode; and a plurality of fluidic channels, including a first fluidic channel and a second fluidic channel, each being configured to form a fluid pathway for allowing a fluid sample to flow through and at least one of the first and second fluidic channels including a cell manipulation portion, the cell manipulation portion including a plurality of constriction portions. The first and second electrode channels are each coupled to the first fluidic channel and the electrodes of the first and second electrode channels and the third and fourth electrode channels are each coupled to the second fluidic channel and the electrodes of the third and fourth electrode channels.

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