公开(公告)号：US20190194710A1

公开(公告)日：2019-06-27

申请号：US16322518

申请日：2017-08-02

Applicant: Spiber Inc.

Inventor： Kenji Kurachi ,  Mihoko Kinoshita

IPC: C12P21/00 ,  C12N5/00 ,  C12N15/63

CPC classification number: C12P21/00 ,  C12N1/00 ,  C12N5/0025 ,  C12N15/635 ,  C12P21/02

Abstract: The invention relates to a method for production of a recombinant protein using recombinant cells that express the recombinant protein under the control of an inducible promoter, the method including continuous culturing with addition of fresh culture medium to a portion of the culture solution in which the recombinant cells have been grown, wherein the recombinant cells whose expression of the recombinant protein has been induced are not reused.