公开(公告)号：US20240369567A1

公开(公告)日：2024-11-07

申请号：US18644592

申请日：2024-04-24

Applicant: Standard BioTools Canada Inc.

Inventor： Alexander V. Loboda ,  Olga Ornatsky ,  Vladimir Baranov ,  Nikita Zabinyakov ,  Anastasia Mavropoulos ,  Daniel Majonis ,  Bedilu Allo ,  Taunia Closson

IPC: G01N33/68 ,  C07K1/13 ,  G01N1/28

Abstract: Embodiments of the present invention relate to reagents and their use for elemental imaging mass spectrometry of biological samples. Embodiments include a method for quantifying one or more analytes within a sample. The method may include providing the sample. One or more analytes may be immobilised to a mass cytometry sample carrier. The sample may have been labelled with one or more mass-tagged SBPs including one or more labelling atoms. The method may include performing mass cytometry on the sample to determine a level of the one or more labelling atoms, where the level of the one or more labelling atoms corresponds to the copy number of the one or more analytes to quantify the analytes.