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    DEVICE AND METHOD FOR RAPIDLY LYSING CELLS OR VIRUSES
    3.
    发明申请
    DEVICE AND METHOD FOR RAPIDLY LYSING CELLS OR VIRUSES 失效
    用于快速诱导细胞或病毒的装置和方法

    公开(公告)号：US20080014122A1

    公开(公告)日：2008-01-17

    申请号：US11560890

    申请日：2006-11-17

    Applicant: Su-hyeon KIM ,  Jeong-gun LEE

    Inventor： Su-hyeon KIM ,  Jeong-gun LEE

    IPC: B01L3/00

    CPC classification number: C12M47/06 ,  B01L3/5027 ,  C12N1/066 ,  C12N13/00 ,  G01N1/44 ,  Y10T137/2496 ,  Y10T436/25

    Abstract: A cell lysis device for lysing cells or viruses, comprising a cell lysis tube having a sample inlet; a pump connected to the cell lysis tube for transferring a sample into the tube; a sealing unit for reversibly sealing a specific region of the tube; and a laser source for generating a laser is provide. Further, a method of lysing cells or viruses using the cell lysis device is provide. The method comprises introducing a sample containing cells or viruses and optionally magnetic beads to the cell lysis tube through the sample inlet; transferring the sample to a specific region in the cell lysis tube by means of the pump; temporarily sealing the region of the cell lysis tube where the sample is placed with the sealing unit; irradiating the sample with the laser; removing the sealing unit from the cell lysis tube; and discharging the sample from the cell lysis tube by means of the pump.

    Abstract translation: 一种用于裂解细胞或病毒的细胞裂解装置，包括具有样品入口的细胞裂解管; 连接到细胞裂解管的泵，用于将样品转移到管中; 用于可逆地密封管的特定区域的密封单元; 并提供用于产生激光的激光源。 此外，提供使用细胞裂解装置裂解细胞或病毒的方法。 该方法包括通过样品入口将含有细胞或病毒的样品和任选的磁珠引入细胞裂解管; 通过泵将样品转移到细胞裂解管中的特定区域; 用密封单元临时密封放置样品的细胞溶解管的区域; 用激光照射样品; 从细胞裂解管中取出密封单元; 并通过泵从细胞裂解管中排出样品。

    DEVICE AND METHOD FOR RAPIDLY LYSING CELLS OR VIRUSES
    4.
    发明申请
    DEVICE AND METHOD FOR RAPIDLY LYSING CELLS OR VIRUSES 失效

    公开(公告)号：US20080182310A1

    公开(公告)日：2008-07-31

    申请号：US12059250

    申请日：2008-03-31

    Applicant: Su-hyeon KIM ,  Jeong-gun LEE

    Inventor： Su-hyeon KIM ,  Jeong-gun LEE

    IPC: C12N13/00

    CPC classification number: C12M47/06 ,  B01L3/5027 ,  C12N1/066 ,  C12N13/00 ,  G01N1/44 ,  Y10T137/2496 ,  Y10T436/25

    Abstract: A cell lysis device for lysing cells or viruses, comprising a cell lysis tube having a sample inlet; a pump connected to the cell lysis tube for transferring a sample into the tube; a sealing unit for reversibly sealing a specific region of the tube; and a laser source for generating a laser is provide. Further, a method of lysing cells or viruses using the cell lysis device is provide. The method comprises introducing a sample containing cells or viruses and optionally magnetic beads to the cell lysis tube through the sample inlet; transferring the sample to a specific region in the cell lysis tube by means of the pump; temporarily sealing the region of the cell lysis tube where the sample is placed with the sealing unit; irradiating the sample with the laser; removing the sealing unit from the cell lysis tube; and discharging the sample from the cell lysis tube by means of the pump.

    OPTICAL DETECTION APPARATUS, OPTICAL DETECTION METHOD, AND MICROFLUIDIC SYSTEM INCLUDING THE OPTICAL DETECTION APPARATUS
    5.
    发明申请
    OPTICAL DETECTION APPARATUS, OPTICAL DETECTION METHOD, AND MICROFLUIDIC SYSTEM INCLUDING THE OPTICAL DETECTION APPARATUS 有权
    光学检测装置，光学检测方法和包括光学检测装置的微流体系统

    公开(公告)号：US20090021741A1

    公开(公告)日：2009-01-22

    申请号：US11972266

    申请日：2008-01-10

    Applicant: Su-hyeon KIM ,  Jeong-gun LEE

    Inventor： Su-hyeon KIM ,  Jeong-gun LEE

    IPC: G01N21/00

    CPC classification number: G01N21/07 ,  G01N21/253 ,  G01N21/276 ,  G01N21/314

    Abstract: Provided are an optical detection apparatus, a microfluidic system including the same, and an optical detection method. The optical detection apparatus including: at least one light emission unit which emits light of a predetermined wavelength band; at least one light receiving unit which is disposed such that the light receiving unit receives the light emitted from the light emission unit and generates an electrical signal according to the intensity of the light received, wherein the number of light receiving units is the same as the number of light emission units; a rotation operating unit which rotates a disk-type microfluidic apparatus comprising at least one detection chamber in which a sample is to be loaded such that the detection chamber is disposed in a light pathway between the light emission unit and the light receiving unit; and a processor which measures a property of the sample contained in the detection chamber using the electrical signal generated by the light receiving unit.

    Abstract translation: 提供了一种光学检测装置，包括该光学检测装置的微流体系统和光学检测方法。 所述光学检测装置包括：发射预定波长带的光的至少一个发光单元; 至少一个光接收单元，其设置成使得所述光接收单元接收从所述发光单元发射的光并根据所接收的光的强度产生电信号，其中所述光接收单元的数量与 发光单位数量; 旋转操作单元，其使包括至少一个检测室的盘式微流体装置旋转，其中样品将被装载，使得检测室设置在发光单元和光接收单元之间的光通路中; 以及处理器，其使用由光接收单元生成的电信号来测量包含在检测室中的样品的性质。

    MICROFLUIDIC VALVE, METHOD OF MANUFACTURING THE SAME, AND MICROFLUIDIC DEVICE COMPRISING THE MICROFLUIDIC VALVE
    7.
    发明申请
    MICROFLUIDIC VALVE, METHOD OF MANUFACTURING THE SAME, AND MICROFLUIDIC DEVICE COMPRISING THE MICROFLUIDIC VALVE 审中-公开
    微流控阀，其制造方法和包含微流控阀的微流体装置

    公开(公告)号：US20110232832A1

    公开(公告)日：2011-09-29

    申请号：US13157535

    申请日：2011-06-10

    Applicant: Jong-myeon PARK ,  Yoon-kyoung CHO ,  Beom-seok LEE ,  Jeong-gun LEE

    Inventor： Jong-myeon PARK ,  Yoon-kyoung CHO ,  Beom-seok LEE ,  Jeong-gun LEE

    IPC: B21K1/20 ,  H05B6/10 ,  B32B37/00

    CPC classification number: F16K99/0001 ,  F16K99/0032 ,  F16K99/004 ,  F16K2099/0084 ,  Y10T29/49412 ,  Y10T137/2191 ,  Y10T137/2196

    Abstract: Provided is a microfluidic valve, a method of manufacturing the microfluidic valve, and a microfluidic device that employs the microfluidic valve. The microfluidic valve includes a platform that includes two substrates combined facing each other; a channel having a first depth allowing a fluid to flow between the two substrates; a valve gap that is disposed on at least a region of the channel and has a second depth which is smaller than the first depth; and a valve plug that is disposed to fill the valve gap and is formed of a valve material made by mixing a phase change material, which is solid at room temperature, with a plurality of exothermic particles that emit an amount of heat sufficient to melt the phase change material by absorbing electromagnetic waves.

    Abstract translation: 本发明提供一种微流体阀，微流体阀的制造方法和采用该微流体阀的微流体装置。 该微流体阀包括一个平台，该平台包括彼此相结合的两个基板; 具有允许流体在两个基板之间流动的第一深度的通道; 阀间隙，其设置在所述通道的至少一个区域上，并且具有小于所述第一深度的第二深度; 以及阀塞，其设置成填充阀间隙，并且由阀室材料形成，所述阀门材料是通过将在室温下为固体的相变材料与多个放出足以熔化的 相变材料通过吸收电磁波。

    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS
    8.
    发明申请
    METHOD AND APPARATUS FOR DISRUPTING CELLS AND AMPLIFYING NUCLEIC ACIDS USING GOLD NANORODS 有权
    破坏细胞的方法和装置，使用金纳多糖放大核酸

    公开(公告)号：US20110212514A1

    公开(公告)日：2011-09-01

    申请号：US13107677

    申请日：2011-05-13

    Applicant: Kwang Ho CHEONG ,  Dong-kee YI ,  Jeong-gun LEE ,  Jong-myeon PARK

    Inventor： Kwang Ho CHEONG ,  Dong-kee YI ,  Jeong-gun LEE ,  Jong-myeon PARK

    IPC: C12M1/00 ,  C12M1/02 ,  C12M1/42

    CPC classification number: C12N1/066 ,  C12M47/06 ,  C12N13/00 ,  C12P19/34

    Abstract: Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an apparatus for continuously disrupting cells and amplifying nucleic acids in a single microchamber are also provided, wherein the method comprises introducing a solution containing cells and gold nanorods into a microchamber, irradiating a laser onto the gold nanorods to disrupt the cells, and amplifying a nucleic acid from the disrupted cells in the microchamber.

    Abstract translation: 提供一种破坏细胞的方法，包括向含有细胞的溶液中加入金纳米棒并用激光照射金纳米棒以破坏细胞。 还提供了用于在单个微室中连续破坏细胞和扩增核酸的方法和装置，其中所述方法包括将含有细胞和金纳米棒的溶液引入微室中，将激光照射到金纳米棒上以破坏细胞，以及 在微室中从破碎的细胞中扩增核酸。

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