公开(公告)号：US20030029274A1

公开(公告)日：2003-02-13

申请号：US10144611

申请日：2002-05-13

Applicant: SurroMed, Inc.

Inventor： Michael J. Natan ,  Michael D. Musick ,  Christine Keating ,  Kenneth R. Brown

IPC: G01J003/44

CPC classification number: B82Y30/00 ,  B01J13/0043 ,  G01N21/658

Abstract: Methods for preparing colloidal metal nanoparticles, in which seed colloids are added to a solution of reductant mixed with a solution containing a source of metal ions, include a method in which the seeds are colloidal gold nanoparticles, the source of gold ions is HAuCl4, and the reductant is NH2OH. SERS substrates are prepared by combining a colloidal gold monolayer with a solution containing a source of metal ions and a reductant such as NH2OH.

Abstract translation: 将种子胶体加入与含有金属离子源的溶液混合的还原剂溶液的制备胶体金属纳米粒子的方法包括其中种子是胶态金纳米颗粒的方法，金离子源是HAuCl4，和 还原剂是NH 2 OH。 通过将胶体金单层与含有金属离子源和还原剂如NH 2 OH的溶液组合来制备SERS底物。