公开(公告)号：US3826615A

公开(公告)日：1974-07-30

申请号：US26148172

申请日：1972-06-09

Applicant: TECHNICON INSTR

Inventor： SMYTHE W ,  BELLINGER S ,  DIEBLER H ,  DANNEWITZ R

IPC: G01F13/00 ,  A61B5/00 ,  G01N1/00 ,  G01N35/08 ,  G01N1/18 ,  G01N33/16

CPC classification number: G01N35/08 ,  Y10T436/118339

Abstract: A FLUID SYSTEM FOR INCLUSION IN AN AUTOMATED FLUID SYSTEM FOR ANALYZING A SERIES OF LIQUID SAMPLES FLOWING SERIATIM, THE FIRST-MENTIONED SYSTEM SERVING TO DILUTE EACH SAMPLE FOR SUBSEQUENT DIVISION INTO A LARGE NUMBER OF PARTS. EACH DILUTEDPART IS INTENDED FOR FLOW TO ONE OF A LARGE NUMBER OF DIFFERENT SUBCOMBINATIONS OF THE TOTAL SYSTEM. IN EACH OF THE SUBCOMBINATIONS THE DILUTED SAMPLE PART MAY RECEIVE A SPECIAL TREATMENT, SUCH AS MIXING WITH APARTICULAR REAGENT OR REAGENTS UNDER CONTROLLED TEMPERATURE CONDITIONS FOR EXAMPLE, PRIOR TO ANALYSIS OF THAT SAMPLE PORTION AS BY PHOTOMETRY FOR EXAMPLE. EACH DILUTED SAMPLE PART MAY BE SUBJECTED TO A DIFFERENT TEST OR ANALYSIS THERE IS INVOLVED IN THE FIRST-MENTIONED SYSTEM THE SAME AND EQUAL DILUTION TREATMENT OF EACH SAMPLE AS THE SERIES. ALSO INVOLVED IN THE FIRST-MENTION SYSTEM IS THE EFFECTIVE INHIBITION OF CROSS CONTAMINATION OF SAMPLES FROM THE POINT OF INTRODUCTION OF THE SAMPLES INTO THE DILUTION SYSTEM TO THE POINT, AFTER DIVISION OF THE SAMPLES AS AFORESAID, WHERE THE SAMPLES FLOW INTO THE RESPECTIVE ONES OF THE AFORESAID ANALYSIS SUBCOMBINATIONS.

公开(公告)号：US3784310A

公开(公告)日：1974-01-08

申请号：US3784310D

申请日：1972-06-07

Applicant: TECHNICON INSTR

Inventor： BARTON S ,  DIEBLER H

IPC: G01N21/27 ,  C23C14/40 ,  G01N35/08 ,  G01N35/10 ,  G01J3/46 ,  G06G7/00

CPC classification number: G01N35/08 ,  G01N2035/1025 ,  Y10T436/118339

Abstract: New and improved system and method for improved operation of a colorimeter or like device are provided and comprise the processing of the colorimeter output data in such manner that a separating fluid-segmented fluid sample stream may be passed through the colorimeter flow cell without adverse effect on said output data. This is accomplished by sampling said output data at periodic intervals and selecting for retention only that of the thusly sampled data which is known to have occurred when the flow cell sight path was filled with a fluid sample segment to the exclusion of the separating fluid segments.

Abstract translation: 提供了改进的色度计或类似装置的操作的新的和改进的系统和方法，并且包括以这样的方式处理色度计输出数据，使得分离流体分段的流体样品流可以通过色度计流动池而不会对 表示输出数据。 这是通过以周期性间隔对所述输出数据进行采样来完成的，并且仅选择已知当流动池视线路径被填充流体样品段以排除分离流体段时已经发生的已被采样的数据的保留。

公开(公告)号：US3811842A

公开(公告)日：1974-05-21

申请号：US26055172

申请日：1972-06-07

Applicant: TECHNICON INSTR

Inventor： DIEBLER H ,  GYORI S ,  MC CANDLESS W

IPC: B01L7/00 ,  G01N35/08 ,  G01N33/16

CPC classification number: B01L7/00 ,  G01N35/08

Abstract: Temperature-controlled fluid manifold for a fluid system of an automated sample analyzer of the type for analyzing a series of liquid samples flowing seriatum to quantitative analysis for a constituent of interest. The basic elements of the temperaturecontrolled manifold may be permanently combined with a wide variety of other components to meet the requirements of many different chemistries to provide many different temperaturecontrolled manifolds each suited for analysis of a different constituent of a sample such as blood for example. In each particular manifold, the sample may be treated as by combination and mixing with any appropriate reagent or reagents under temperature-controlled conditions for subsequent analysis as in a colorimeter for example. The manifold may be significantly smaller in size and less costly than conventional manifolds. The aforementioned basic manifold elements comprise a thermally conductive plate or block heated by conduction from a temperature-controlled source of heat, which plate has an outer, exposed surface of substantial area, and an appropriate number of appropriately configured fluid passageway portions, such as helical mixing or helical time-delay paths, encapsulated in a solid material characterized by a heat storage capacity and which material is supported in an appropriate location on the lastmentioned surface for thermal transfer by conduction to the material from the plate. The manifold includes a cover effectively tending to stagnate the ambient atmosphere around such encapsulated fluid passageway portions.