Abstract:
Liquid from a liquid sample container is flowed in automated analysis apparatus into a filter-equipped inlet end of a probe while the latter is immersed in the liquid, for transport of the sample to automated analysis. The probe is subsequently removed from the container and immersed in the liquid of a wash receptacle. Prior to immersion in another liquid sample, a fluid, other than sample, is flushed through the aforementioned filter in a reverse direction to cleanse it of particulate matter, the flushing being in timed relation to the movements of the probe.
Abstract:
Temperature-controlled fluid manifold for a fluid system of an automated sample analyzer of the type for analyzing a series of liquid samples flowing seriatum to quantitative analysis for a constituent of interest. The basic elements of the temperaturecontrolled manifold may be permanently combined with a wide variety of other components to meet the requirements of many different chemistries to provide many different temperaturecontrolled manifolds each suited for analysis of a different constituent of a sample such as blood for example. In each particular manifold, the sample may be treated as by combination and mixing with any appropriate reagent or reagents under temperature-controlled conditions for subsequent analysis as in a colorimeter for example. The manifold may be significantly smaller in size and less costly than conventional manifolds. The aforementioned basic manifold elements comprise a thermally conductive plate or block heated by conduction from a temperature-controlled source of heat, which plate has an outer, exposed surface of substantial area, and an appropriate number of appropriately configured fluid passageway portions, such as helical mixing or helical time-delay paths, encapsulated in a solid material characterized by a heat storage capacity and which material is supported in an appropriate location on the lastmentioned surface for thermal transfer by conduction to the material from the plate. The manifold includes a cover effectively tending to stagnate the ambient atmosphere around such encapsulated fluid passageway portions.