公开(公告)号：US20190284252A1

公开(公告)日：2019-09-19

申请号：US16356872

申请日：2019-03-18

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS

Inventor： Suresh Kumar Thallapuranam ,  Shilpi Agarwal ,  Ravi Kumar Gindampati ,  Srinivas Jayanthi ,  Tengjiao Wang ,  Jake Jones ,  Olivia Kolenc ,  Ngoc Lam ,  Isabelle Niyonshuti ,  Kartik Balachandran ,  Kyle Quinn ,  Jingyi Chen

IPC: C07K14/50 ,  A61K9/06

Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.

公开(公告)号：US20220227826A1

公开(公告)日：2022-07-21

申请号：US17587889

申请日：2022-01-28

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS

Inventor： Suresh Kumar Thallapuranam ,  Shilpi Agrawal ,  Ravi Kumar Gundampati ,  Srinivas Jayanthi ,  Tengjiao Wang ,  Jake Jones ,  Olivia Kolenc ,  Ngoc Lam ,  Isabelle Niyonshuti ,  Kartik Balachandran ,  Kyle Quinn ,  Jingyi Chen

IPC: C07K14/50 ,  A61K9/06

Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.

公开(公告)号：US11267855B2

公开(公告)日：2022-03-08

申请号：US16356872

申请日：2019-03-18

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS

Inventor： Suresh Kumar Thallapuranam ,  Shilpi Agarwal ,  Ravi Kumar Gundampati ,  Srinivas Jayanthi ,  Tengjiao Wang ,  Jake Jones ,  Olivia Kolenc ,  Ngoc Lam ,  Isabelle Niyonshuti ,  Kartik Balachandran ,  Kyle Quinn ,  Jingyi Chen

IPC: C07K14/50 ,  A61K9/06 ,  A61K38/00 ,  A61K38/18

Abstract: Engineered FGF1 and FGF2 polypeptides, polynucleotides encoding these polypeptides and DNA constructs, vectors and compositions including these engineered polypeptides are provided herein. The engineered FGF1 and FGF2 polypeptides are more stable than their wild-type counterparts and may be more effective at treating a variety of conditions that FGF1 and FGF2 are useful for treating such as wound healing.