公开(公告)号：US20250121190A1

公开(公告)日：2025-04-17

申请号：US18986810

申请日：2024-12-19

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Andre Machado ,  Raghavan Gopalakrishnan ,  Kenneth Baker

IPC: A61N1/36 ,  A61N1/05

Abstract: Deep brain stimulation (DBS) can be used to treat many neurological conditions beyond traditional movement disorders. When patients do not suffer from traditional movement disorders, medical professionals cannot use traditional observation-based methods to configure the DBS system. A new method for selecting stimulation configurations can include recording internal data and external data as the patient performs (or attempts to perform) a motor task. The internal data is electrophysiology data recorded by a plurality of DBS electrodes, used to identify at least one of the plurality of electrodes closest to a neuronal population involved in control of the at least one motor task. The external data is electroencephalogram (EEG) data recorded by scalp electrodes, which is used to select at least one of the potential stimulation electrodes to deliver the DBS. When the electrode(s) delivering the DBS are selected, optimal parameters for the DBS are then chosen.

公开(公告)号：US20210228880A1

公开(公告)日：2021-07-29

申请号：US17154045

申请日：2021-01-21

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Andre Machado ,  Raghavan Gopalakrishnan ,  Kenneth Baker

IPC: A61N1/36 ,  A61N1/05

Abstract: Deep brain stimulation (DBS) can be used to treat many neurological conditions beyond traditional movement disorders. When patients do not suffer from traditional movement disorders, medical professionals cannot use traditional observation-based methods to configure the DBS system. A new method for selecting stimulation configurations can include recording internal data and external data as the patient performs (or attempts to perform) a motor task. The internal data is electrophysiology data recorded by a plurality of DBS electrodes, used to identify at least one of the plurality of electrodes closest to a neuronal population involved in control of the at least one motor task. The external data is electroencephalogram (EEG) data recorded by scalp electrodes, which is used to select at least one of the potential stimulation electrodes to deliver the DBS. When the electrode(s) delivering the DBS are selected, optimal parameters for the DBS are then chosen.

公开(公告)号：US12194297B2

公开(公告)日：2025-01-14

申请号：US17154045

申请日：2021-01-21

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Andre Machado ,  Raghavan Gopalakrishnan ,  Kenneth Baker

IPC: A61N1/36 ,  A61N1/05

Abstract: Deep brain stimulation (DBS) can be used to treat many neurological conditions beyond traditional movement disorders. When patients do not suffer from traditional movement disorders, medical professionals cannot use traditional observation-based methods to configure the DBS system. A new method for selecting stimulation configurations can include recording internal data and external data as the patient performs (or attempts to perform) a motor task. The internal data is electrophysiology data recorded by a plurality of DBS electrodes, used to identify at least one of the plurality of electrodes closest to a neuronal population involved in control of the at least one motor task. The external data is electroencephalogram (EEG) data recorded by scalp electrodes, which is used to select at least one of the potential stimulation electrodes to deliver the DBS. When the electrode(s) delivering the DBS are selected, optimal parameters for the DBS are then chosen.