公开(公告)号：US20160161409A1

公开(公告)日：2016-06-09

申请号：US14906789

申请日：2014-06-20

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Aydogan Ozcan ,  Zoltan Gorocs ,  Yuye Ling ,  Meng Dai Yu

IPC: G01N21/64 ,  G01N33/58

CPC classification number: G01N21/6458 ,  G01N15/1434 ,  G01N15/1456 ,  G01N21/6456 ,  G01N33/50 ,  G01N33/582 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/068 ,  G01N2201/101

Abstract: A scanning system for fluorescent imaging includes a sample holder configured to hold a sample therein, the sample holder defining a sample holding region. A scanner head spans the sample holding region and is movable relative to the sample holder. An array of light sources is disposed on an opposing side of the sample holder and is angled relative thereto. Respective controller are operably coupled to the scanner head and the array of light sources, wherein one controller selectively actuates a one or more rows of the array of light sources and another controller controls movement of the scanner head to capture fluorescent light emitted from within the sample holder in response to illumination from the actuated light sources. A filter designed to filter out scattered light from the sample may be interposed between the sample holder and the scanner head.

Abstract translation: 用于荧光成像的扫描系统包括被配置为将样本保持在其中的样本保持器，所述样本保持器限定样本保持区域。 扫描器头跨越样品保持区域并且可相对于样品保持器移动。 光源阵列设置在样品保持器的相对侧并且相对于其倾斜。 相应的控制器可操作地耦合到扫描仪头部和光源阵列，其中一个控制器选择性地致动光源阵列的一行或多行，另一个控制器控制扫描器头部的移动以捕获从样品内发射的荧光 响应于来自致动光源的照明。 用于过滤来自样品的散射光的滤光器可以插入在样品架和扫描仪头之间。

公开(公告)号：US09683938B2

公开(公告)日：2017-06-20

申请号：US14906789

申请日：2014-06-20

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Aydogan Ozcan ,  Zoltan Gorocs ,  Yuye Ling ,  Meng Dai Yu

IPC: G02B26/08 ,  G01N21/64 ,  G01N33/50 ,  G01N15/14 ,  G01N33/58

CPC classification number: G01N21/6458 ,  G01N15/1434 ,  G01N15/1456 ,  G01N21/6456 ,  G01N33/50 ,  G01N33/582 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/068 ,  G01N2201/101

Abstract: A scanning system for fluorescent imaging includes a sample holder configured to hold a sample therein, the sample holder defining a sample holding region. A scanner head spans the sample holding region and is movable relative to the sample holder. An array of light sources is disposed on an opposing side of the sample holder and is angled relative thereto. Respective controller are operably coupled to the scanner head and the array of light sources, wherein one controller selectively actuates a one or more rows of the array of light sources and another controller controls movement of the scanner head to capture fluorescent light emitted from within the sample holder in response to illumination from the actuated light sources. A filter designed to filter out scattered light from the sample may be interposed between the sample holder and the scanner head.