公开(公告)号：US20180243469A1

公开(公告)日：2018-08-30

申请号：US15753556

申请日：2016-08-31

Applicant: THE UNIVERSITY OF SYDNEY

Inventor： Ali Fathi ,  Fariba Dehghani ,  Anthony Weiss ,  Suzannne Mithieux

IPC: A61L27/16 ,  C08F220/28 ,  C08L33/26 ,  C08L89/00 ,  A61K9/00 ,  A61K31/787 ,  A61L27/54 ,  A61L27/52 ,  A61K38/39 ,  A61L27/24 ,  A61L27/58 ,  A61L27/22 ,  A61K38/17 ,  A61F2/28

CPC classification number: A61L27/16 ,  A61F2/28 ,  A61F2002/2817 ,  A61K9/0019 ,  A61K31/787 ,  A61K38/1709 ,  A61K38/39 ,  A61K47/32 ,  A61K47/42 ,  A61L27/227 ,  A61L27/24 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/252 ,  A61L2300/412 ,  A61L2400/06 ,  A61L2430/02 ,  C08F220/28 ,  C08F2220/285 ,  C08L33/14 ,  C08L33/26 ,  C08L89/00 ,  C08L2201/06 ,  C08L2201/54 ,  C08L2203/02

Abstract: Disclosed herein are biocompatible materials useful for tissue regeneration and repair, wherein the bioactive polymer may be in the form of a hydrogel, for example a thermoresponsive hydrogel. This bioactive polymer and a resulting hydrogel, may be used for the regeneration of bone tissue. Accordingly, also disclosed herein are methods of treating a bone defect in a mammal, the methods comprising administering a therapeutically effective amount of a hydrogel formed by the bioactive polymer to the mammal to treat the bone defect.