公开(公告)号：US20240218418A1

公开(公告)日：2024-07-04

申请号：US18600975

申请日：2024-03-11

Applicant: TOPPAN HOLDINGS INC.

Inventor： Isana NADA ,  Rii MORIMURA ,  Shiro KITANO

IPC: C12Q1/02 ,  C12N5/071 ,  C12N5/0783 ,  C12N5/09

CPC classification number: C12Q1/02 ,  C12N5/0638 ,  C12N5/069 ,  C12N5/0693

Abstract: A method for evaluating migration ability of migratory cells includes culturing a cell structure having a stromal cell layer containing migratory and stromal cells, and a migratory cell-free cell layer containing no migratory cells, and evaluating migration ability of the migratory cells based on mobility of the migratory cells. The mobility is a ratio of height Hm of the migratory cells to height Hs of the cell structure, the height Hm is distance between point Pb and the migratory cells, the point Pb is intersection where a perpendicular line down from the migratory cells to bottom of the cell structure intersects the bottom of the cell structure, the height Hs is distance between the point Pb and point Pt, the point Pt is an intersection where a straight line obtained by extending the perpendicular line to top surface of the cell structure intersects the top surface of the cell structure.