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公开(公告)号：US20240374421A1
公开(公告)日：2024-11-14
申请号：US18196849
申请日：2023-05-12
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Timothy Stowe
Abstract: A non-gravitational fluid delivery device is provided for delivering fluid to an eye of a user. The device has a cartridge including a container and a cartridge head coupled to the container. The container defines an inner container chamber configured to accommodate a fluid. The head includes opposing first and second walls collectively defining both a nozzle and a nozzle opening extending through the nozzle. The first wall is at least partially formed from a deformable material. The second wall is at least partially formed from a rigid material. Fluid is selectively delivered from the fluid delivery device to the eye through the nozzle opening. The nozzle opening extends in a fluid delivery direction between the first and second walls. The nozzle opening is selectively transitioned between opened and closed conditions via selective manipulation of the first wall.
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公开(公告)号：US20230089768A1
公开(公告)日：2023-03-23
申请号：US18059172
申请日：2022-11-28
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Timothy Stowe
Abstract: A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.
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3.发明公开公开(公告)号：US20240041644A1
公开(公告)日：2024-02-08
申请号：US18230014
申请日：2023-08-03
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Timothy Stowe
IPC: A61F9/00
CPC classification number: A61F9/0008 , A61F2250/0096 , A61F2250/0068
Abstract: An ophthalmic applicator for treating an eye of a user includes a housing and a reservoir, supported by the housing, for containing a liquid for treating the eye. The applicator also includes a nozzle supported by the housing and operatively connected to the reservoir. The nozzle is configured a non-gravitationally directed dose of the liquid. The applicator further includes a proximity sensor configured to identify the eye, left or right, to which the applicator is applying the liquid to the eye of the user.
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公开(公告)号：US11723797B2
公开(公告)日：2023-08-15
申请号：US18059172
申请日：2022-11-28
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Timothy Stowe
CPC classification number: A61F9/0008 , A61L2/10 , A61L2/26 , A61B5/1103 , A61F2210/0071 , A61L2202/11 , A61L2202/24
Abstract: A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.
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公开(公告)号：US11707381B2
公开(公告)日：2023-07-25
申请号：US17319987
申请日：2021-05-13
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Timothy Stowe
IPC: A61F9/00
CPC classification number: A61F9/0026 , A61F9/0008 , A61F9/0017 , A61M2210/0612
Abstract: A fluid dispensing device includes a light source, and a nozzle spaced from the light source. The device also includes a membrane positioned within a beam path of the light source, where the membrane is configured to allow a portion of light from the light source through to the nozzle. The device also includes a fluid chamber positioned between the membrane and the nozzle, where the nozzle is configured to allow a beam of the portion of light to pass through along the beam path, and where the nozzle is further configured to form a stream of fluid expelled from the fluid chamber along the beam path.
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Patent Agency Ranking
公开(公告)号：US20230001207A1
公开(公告)日：2023-01-05
申请号：US17940433
申请日：2022-09-08
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Dimitri Azar , Fred Shungneng Lee , Timothy Stowe
Abstract: According to some aspects, a device is presented herein that is configured to be located underneath an eyelid and worn by a user for treating dry eye. The device includes a first surface configured to face a portion of a sclera of the eye, and a second surface configured to face an eyelid and to be completely covered by the eyelid. In some embodiments, the device further includes a plurality of stimulation electrodes proximal to the first surface, wherein the plurality of stimulation electrodes is configured to stimulate the sclera. The device further includes an energy storage element coupled to the plurality of stimulation electrodes. The energy storage element is configured to supply power to the plurality of stimulation electrodes. The device further includes a processor configured to control a supply of energy from the energy storage element to the plurality of stimulation electrodes to stimulate the sclera.
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公开(公告)号：US11446495B2
公开(公告)日：2022-09-20
申请号：US15931241
申请日：2020-05-13
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Dimitri Azar , Fred Shungneng Lee , Timothy Stowe
Abstract: According to some aspects, a device is presented herein that is configured to be located underneath an eyelid and worn by a user for treating dry eye. The device includes a first surface configured to face a portion of a sclera of the eye, and a second surface configured to face an eyelid and to be completely covered by the eyelid. In some embodiments, the device further includes a plurality of stimulation electrodes proximal to the first surface, wherein the plurality of stimulation electrodes is configured to stimulate the sclera. The device further includes an energy storage element coupled to the plurality of stimulation electrodes. The energy storage element is configured to supply power to the plurality of stimulation electrodes. The device further includes a processor configured to control a supply of energy from the energy storage element to the plurality of stimulation electrodes to stimulate the sclera.
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公开(公告)号：US20240207639A1
公开(公告)日：2024-06-27
申请号：US18544122
申请日：2023-12-18
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Dimitri Azar , Timothy Stowe
CPC classification number: A61N5/0625 , A61H23/02 , A61H2201/0207 , A61H2201/1418 , A61H2201/5082 , A61N2005/005 , A61N2005/0626 , A61N2005/0635 , A61N2005/0652 , A61N2005/0659 , A61N2005/0666
Abstract: Systems, devices and methods that facilitate safe heating of eyelids to treat dry eye are disclosed. According to one embodiment, an apparatus for optical heating of an eyelid of a patient includes: a housing configured to be grasped by a human hand; at least one light emitter coupled to the housing and configured to emit beams of infrared light; a waveguide component coupled to the at least one light emitter and configured to direct the beams of light toward the eyelid; and a scleral cover configured to couple to the housing, the scleral cover comprising: a curved protective portion configured to reflect infrared light emanating from the at least one light emitter.
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公开(公告)号：US20240173167A1
公开(公告)日：2024-05-30
申请号：US18449450
申请日：2023-08-14
Applicant: Twenty Twenty Therapeutics LLC
Inventor： Timothy Stowe
CPC classification number: A61F9/0008 , A61L2/10 , A61L2/26 , A61B5/1103 , A61L2202/24
Abstract: A fluid dispensing device includes a cartridge comprising a housing and a head coupled to the housing. The housing forms a first chamber configured to accommodate a fluid; and the head includes a nozzle; and an elastomeric wall that is spaced from the nozzle to form a holding chamber. The holding chamber is in fluid communication with the first chamber and configured to accommodate a portion of the fluid; and the nozzle forms one or more openings to eject the portion of the fluid from the holding chamber. The one or more openings form an oblong shape such that a length of the oblong shape is greater than a width of the oblong shape. The one or more openings can include two parallel slots that together form the oblong shape.
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公开(公告)号：US20240148548A1
公开(公告)日：2024-05-09
申请号：US18387004
申请日：2023-11-03
Applicant: TWENTY TWENTY THERAPEUTICS LLC
Inventor： Timothy Stowe
IPC: A61F9/00
CPC classification number: A61F9/0008
Abstract: A nozzle for a fluid delivery device includes a nozzle head. The nozzle head defines an inner head chamber for a fluid. The nozzle head has at least one nozzle opening through which fluid is configured to be selectively delivered from the head chamber to a target site during use of the device. The nozzle head is at least partially formed from a deformable material. The nozzle head is selectively deflectable between an opened condition in which the at least one nozzle opening is at least partially open to permit fluid flow therethrough and a closed condition in which the at least one nozzle opening is at least partially closed to restrict fluid flow therethrough.
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