公开(公告)号：US11951232B2

公开(公告)日：2024-04-09

申请号：US16903920

申请日：2020-06-17

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Kathleen Derwin ,  Amit Aurora ,  Joseph P. Iannotti ,  Jesse A. McCarron

IPC: A61L27/36 ,  A61F2/08 ,  A61L27/40 ,  A61L27/54 ,  A61F2/00

CPC classification number: A61L27/3633 ,  A61F2/08 ,  A61L27/40 ,  A61L27/54 ,  A61F2/0063 ,  A61L27/3604

Abstract: One aspect of the present disclosure can include a biocompatible tissue graft. The graft can include an extracellular matrix (ECM) patch or strip and at least one fiber stitched into the ECM patch or strip in a peripheral reinforcement pattern. The at least one fiber can have opposing terminal ends. The at least one fiber can mitigate tearing and/or improve fixation retention of the ECM patch or strip. The at least one fiber can comprise a plurality of interconnected stitches. The opposing terminal ends of the at least one fiber can be stitched together to form a continuous stitching construction.

公开(公告)号：US20180311411A9

公开(公告)日：2018-11-01

申请号：US14097328

申请日：2013-12-05

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Kathleen Derwin ,  Amit Aurora ,  Joseph P. Iannotti ,  Jesse A. McCarron

IPC: A61L27/40 ,  A61L27/54

Abstract: A biocompatible tissue graft is provided. The tissue graft includes an extracellular matrix patch and a means for reinforcing the patch.

公开(公告)号：US20200316256A1

公开(公告)日：2020-10-08

申请号：US16903920

申请日：2020-06-17

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Kathleen Derwin ,  Amit Aurora ,  Joseph P. Iannotti ,  Jesse A. McCarron

IPC: A61L27/36 ,  A61F2/08 ,  A61L27/40 ,  A61L27/54

Abstract: One aspect of the present disclosure can include a biocompatible tissue graft. The graft can include an extracellular matrix (ECM) patch or strip and at least one fiber stitched into the ECM patch or strip in a peripheral reinforcement pattern. The at least one fiber can have opposing terminal ends. The at least one fiber can mitigate tearing and/or improve fixation retention of the ECM patch or strip. The at least one fiber can comprise a plurality of interconnected stitches. The opposing terminal ends of the at least one fiber can be stitched together to form a continuous stitching construction.

公开(公告)号：US10758644B2

公开(公告)日：2020-09-01

申请号：US14097328

申请日：2013-12-05

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Kathleen Derwin ,  Amit Aurora ,  Joseph P. Iannotti ,  Jesse A. McCarron

IPC: A61L27/36 ,  A61F2/00 ,  A61F2/08 ,  A61L27/40 ,  A61L27/54

Abstract: A biocompatible tissue graft is provided. The tissue graft includes an extracellular matrix patch and a means for reinforcing the patch.

公开(公告)号：US20240386570A1

公开(公告)日：2024-11-21

申请号：US18667194

申请日：2024-05-17

Applicant: The Cleveland Clinic Foundation

Inventor： Mingrui Yang ,  Bong-Jae Jun ,  Joshua Polster ,  Carl Winalski ,  Kathleen Derwin ,  Eric T. Ricchetti ,  Xiaojuan Li ,  Nicolas Piuzzi

IPC: G06T7/10 ,  A61B5/00 ,  A61B5/107 ,  G06T7/00 ,  G06T7/62 ,  G06V10/26 ,  G06V10/28 ,  G06V10/764 ,  G16H50/50

Abstract: A muscle segmentation method and system utilizes a trained machine learning system to identify and segment skeletal muscle from input magnetic resonance images of the shoulder. Properties of the muscle can be determined from the segmentation, and clinical treatment decisions can be more accurately made based on the determined properties.

公开(公告)号：US20140094931A1

公开(公告)日：2014-04-03

申请号：US14097328

申请日：2013-12-05

Applicant: THE CLEVELAND CLINIC FOUNDATION

Inventor： Kathleen Derwin ,  Amit Aurora ,  Joseph P. Iannotti ,  Jesse A. McCarron

IPC: A61L27/40 ,  A61L27/54

Abstract: A biocompatible tissue graft is provided. The tissue graft includes an extracellular matrix patch and a means for reinforcing the patch.

Abstract translation: 提供生物相容性组织移植物。 组织移植物包括细胞外基质贴片和用于加强贴片的装置。